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CD40 Antikörper (PE)

CD40 Reaktivität: Maus FACS Wirt: Ratte Monoclonal PE

Produktnummer ABIN133944

Datenblatt (PDF)

Target Alle CD40 Antikörper anzeigen

CD40
Reaktivität
189

109

21

20

6

6

4

4

4

4

2

2

2

2

2

1
Maus
Wirt
107

98

51

6

2

1

1
Ratte
Passende Sekundärantikörper
Klonalität
171

88

5
Monoklonal
Konjugat
121

24

21

19

12

8

7

4

4

4

4

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD40 Antikörper ist konjugiert mit PE
Applikation
149

96

63

53

32

26

19

19

16

14

13

13

8

6

5

5

4

4

4

3

3

3

2

2

2

2

2

1

1

1

1
Flow Cytometry (FACS)

Spezifität

Mouse CD40

Immunogen

mouse CD40-human IgG1 fusion protein

Isotyp

IgG2a

Top Product

Discover our top product CD40 Primärantikörper
anti-CD40 (CD40) (AA 26-187) antibody
CD40 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-CD40 (CD40) antibody
CD40 Reaktivität: Human FACS, IHC, IF, StM, DNA Mic Wirt: Maus Monoclonal C40-1605 unconjugated

anti-CD40 (CD40) antibody
CD40 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD40 (CD40) (AA 21-193) antibody
CD40 Reaktivität: Human FACS, WB, ELISA, IHC, ICC, Neut Wirt: Maus Monoclonal 4E1B9 unconjugated

anti-CD40 (CD40) (AA 29-107) antibody
CD40 Reaktivität: Human FACS, ELISA, IHC, StM, Coat Wirt: Maus Monoclonal C40-2383 unconjugated

anti-CD40 (CD40) (C-Term) antibody
CD40 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-CD40 (CD40) (AA 71-187) antibody
CD40 Reaktivität: Human WB, IF Wirt: Maus Monoclonal 41-CD40 unconjugated

anti-CD40 (CD40) (AA 1-360) antibody
CD40 Reaktivität: Human, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-CD40 (CD40) (Extracellular Domain) antibody
CD40 Reaktivität: Human FACS, IHC, St Wirt: Maus Monoclonal 5C3 unconjugated

anti-CD40 (CD40) antibody (FITC)
CD40 Reaktivität: Human FACS Wirt: Maus Monoclonal HI40a FITC

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

0.1 mg/ml

Lagerung

4 °C
Target

CD40

Andere Bezeichnung

CD40 (CD40 Produkte)

Synonyme

Bp50 antikoerper, CDW40 antikoerper, TNFRSF5 antikoerper, p50 antikoerper, AI326936 antikoerper, GP39 antikoerper, HIGM1 antikoerper, IGM antikoerper, IMD3 antikoerper, T-BAM antikoerper, TRAP antikoerper, Tnfrsf5 antikoerper, TNFSF5 antikoerper, CD40 molecule antikoerper, CD40 antigen antikoerper, CD40 antikoerper, Cd40 antikoerper

Hintergrund

Anti-mouse monoclonal antibody (clone 3/23) reacts with CD40 which is expressed on B lymphocytes and on a subset of both CD4 and CD8 T cells in the adult (but not neonatal) spleen . The level of CD40 on B cells is enhanced following activation by LPS . The interactions of CD40 with its ligand CD40L are responsible for generating humoral responses, germinal center formation, and generating B cell memory . Stimulating cells with immobilized 3/23 mAb in- creases expression of CD86 (B7.2) on B cells 1,3 . Though the 3/23 mAb itself is a weak mitogen, it produces a synergistic proliferative B cell response with IL-4 or with mitogenic antibodies against surface Ig 1,3 . Costimulation with 3/23 mAb and IL-4 rescues B cells from apoptosis induced by hypercross-linking of sIgM or sIgD The 3/23 clone is suitable for use in flow cytometry. This clone is reported to be suitable for use in immunohistochemistry of acetone fixed frozen tissue sections

Pathways

NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints