CD40 Antikörper
-
- Target Alle CD40 Antikörper anzeigen
- CD40
-
Reaktivität
- Maus
-
Wirt
- Ratte
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CD40 Antikörper ist unkonjugiert
-
Applikation
- Flow Cytometry (FACS)
- Spezifität
- Mouse CD40
- Aufreinigung
- Purified
- Isotyp
- IgG2a
- Top Product
- Discover our top product CD40 Primärantikörper
-
-
- Applikationshinweise
- This antibody is suitable for use in flow cytometry.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 0.2 mg/ml
- Lagerung
- 4 °C
-
- Target
- CD40
- Andere Bezeichnung
- CD40 (CD40 Produkte)
- Synonyme
- Bp50 antikoerper, CDW40 antikoerper, TNFRSF5 antikoerper, p50 antikoerper, AI326936 antikoerper, GP39 antikoerper, HIGM1 antikoerper, IGM antikoerper, IMD3 antikoerper, T-BAM antikoerper, TRAP antikoerper, Tnfrsf5 antikoerper, TNFSF5 antikoerper, CD40 molecule antikoerper, CD40 antigen antikoerper, CD40 antikoerper, Cd40 antikoerper
- Hintergrund
- Anti-mouse monoclonal antibody reacts with CD40 which is expressed on B lymphocytes and on a subset of both CD4 and CD8 T cells in the adult (but not neonatal) spleen . The level of CD40 on B cells is enhanced following activation by LPS . The interactions of CD40 with its ligand CD40L are responsible for generating humoral responses, germinal centre formation, and generating B cell memory . Stimulating cells with immobilized 3/23 mAb increases expression of CD86(B7.2) on B cells 1,3 . Though the 3/23 mAb itself is a weak mitogen, it produces a synergistic proliferative B cell response with IL-4 or with mitogenic antibodies against surface Ig 1,3 . Costimulation with 3/23 mAb and IL-4 rescues B cells from apoptosis induced by hypercross-linking of sIgM or sIgD . Other applications of the 3/23 mAb include IHC of acetone-fixed frozen sections This antibody is suitable for use in flow cytometry.
- Pathways
- NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
-