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CD40 Antikörper

CD40 Reaktivität: Maus FACS Wirt: Ratte Monoclonal unconjugated
Produktnummer ABIN133941
  • Target Alle CD40 Antikörper anzeigen
    CD40
    Reaktivität
    • 192
    • 110
    • 22
    • 20
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Maus
    Wirt
    • 107
    • 100
    • 51
    • 6
    • 2
    • 1
    • 1
    • 1
    Ratte
    Klonalität
    • 173
    • 89
    • 5
    Monoklonal
    Konjugat
    • 124
    • 24
    • 21
    • 19
    • 12
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD40 Antikörper ist unkonjugiert
    Applikation
    • 151
    • 97
    • 64
    • 54
    • 32
    • 28
    • 20
    • 19
    • 17
    • 14
    • 13
    • 13
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    Mouse CD40
    Aufreinigung
    Purified
    Isotyp
    IgG2a
    Top Product
    Discover our top product CD40 Primärantikörper
  • Applikationshinweise
    This antibody is suitable for use in flow cytometry.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.2 mg/ml
    Lagerung
    4 °C
  • Target
    CD40
    Andere Bezeichnung
    CD40 (CD40 Produkte)
    Synonyme
    Bp50 antikoerper, CDW40 antikoerper, TNFRSF5 antikoerper, p50 antikoerper, AI326936 antikoerper, GP39 antikoerper, HIGM1 antikoerper, IGM antikoerper, IMD3 antikoerper, T-BAM antikoerper, TRAP antikoerper, Tnfrsf5 antikoerper, TNFSF5 antikoerper, CD40 molecule antikoerper, CD40 antigen antikoerper, CD40 antikoerper, Cd40 antikoerper
    Hintergrund
    Anti-mouse monoclonal antibody reacts with CD40 which is expressed on B lymphocytes and on a subset of both CD4 and CD8 T cells in the adult (but not neonatal) spleen . The level of CD40 on B cells is enhanced following activation by LPS . The interactions of CD40 with its ligand CD40L are responsible for generating humoral responses, germinal centre formation, and generating B cell memory . Stimulating cells with immobilized 3/23 mAb increases expression of CD86(B7.2) on B cells 1,3 . Though the 3/23 mAb itself is a weak mitogen, it produces a synergistic proliferative B cell response with IL-4 or with mitogenic antibodies against surface Ig 1,3 . Costimulation with 3/23 mAb and IL-4 rescues B cells from apoptosis induced by hypercross-linking of sIgM or sIgD . Other applications of the 3/23 mAb include IHC of acetone-fixed frozen sections This antibody is suitable for use in flow cytometry.
    Pathways
    NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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