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SMAD4 Antikörper

SMAD4 Reaktivität: Human WB, IF Wirt: Maus Monoclonal IMD-89 unconjugated
Produktnummer ABIN1109062
  • Target Alle SMAD4 Antikörper anzeigen
    SMAD4 (SMAD Family Member 4 (SMAD4))
    Reaktivität
    • 101
    • 42
    • 37
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 90
    • 11
    • 1
    Maus
    Klonalität
    • 76
    • 26
    Monoklonal
    Konjugat
    • 58
    • 9
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SMAD4 Antikörper ist unkonjugiert
    Applikation
    • 67
    • 46
    • 36
    • 30
    • 22
    • 13
    • 9
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Spezifität
    This antibody reacts to SMAD4.
    Aufreinigung
    Affinity chromatography
    Immunogen
    Recombinant human Smad4 (DPC4).
    Klon
    IMD-89
    Isotyp
    IgG1
    Top Product
    Discover our top product SMAD4 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Restore with 1.2 % sodium acetate or neutral PBS
    Konzentration
    0,1 mg/mL
    Buffer
    1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    SMAD4 (SMAD Family Member 4 (SMAD4))
    Andere Bezeichnung
    SMAD4 (SMAD4 Produkte)
    Synonyme
    smad4 antikoerper, DPC4 antikoerper, JIP antikoerper, MADH4 antikoerper, MYHRS antikoerper, AW743858 antikoerper, D18Wsu70e antikoerper, Madh4 antikoerper, XSmad4alpha antikoerper, Xsmad4 antikoerper, dpc4 antikoerper, jip antikoerper, madh4 antikoerper, xsmad4a antikoerper, SMAD family member 4 antikoerper, Smad4 protein antikoerper, SMAD family member 4, gene 1 L homeolog antikoerper, SMAD4 antikoerper, smad4 antikoerper, Smad4 antikoerper, smad4.1.L antikoerper
    Hintergrund
    SMAD4 plays a pivotal role in signal transduction of the transforming growth factor beta superfamily cytokines by mediating transcriptional activation of target genes. Smad4 signalling in T cells is required for suppression of gastrointestinal cancer. Mutational inactivation of SMAD4 causes TGF-beta unresponsiveness and gave a basis for understanding the physiologic role of this gene in tumorigenesis. Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases.Synonyms: DPC4, Deletion target in pancreatic carcinoma 4, MAD homolog 4, MADH4, Mothers against DPP homolog 4, Mothers against decapentaplegic homolog 4, SMAD 4, SMAD family member 4, SMAD-4
    Gen-ID
    4089
    NCBI Accession
    NP_005350
    UniProt
    Q13485
    Pathways
    Zellzyklus, Chromatin Binding, Autophagie
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