SMAD4 Antikörper (AA 400-428)
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- Target Alle SMAD4 Antikörper anzeigen
- SMAD4 (SMAD Family Member 4 (SMAD4))
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Bindungsspezifität
- AA 400-428
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SMAD4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat, Bovine, Pig
- Aufreinigung
- Purified
- Immunogen
- A portion of amino acids 400-428 from the human protein was used as the immunogen for this SMAD4 antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product SMAD4 Primärantikörper
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anti-SMAD Family Member 4 (SMAD4) (N-Term) antibody
SMAD4 Reaktivität: Human WB, IP, CUT&RUN Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 1-552) antibodySMAD4 Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 3E2 unconjugated
anti-SMAD Family Member 4 (SMAD4) antibodyKO Validated SMAD4 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Monoclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 255-284) antibodySMAD4 Reaktivität: Human, Maus WB, IF Wirt: Kaninchen Polyclonal RB14714 unconjugated
anti-SMAD Family Member 4 (SMAD4) antibodySMAD4 Reaktivität: Human WB, ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 4G1C6 unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 40-120) antibodySMAD4 Reaktivität: Human, Maus, Ratte, Affe WB, ELISA, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 27-195) antibodySMAD4 Reaktivität: Human WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 400-428), (C-Term) antibodySMAD4 Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB20720 unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 118-240) antibodySMAD4 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (pThr277) antibodySMAD4 Reaktivität: Human ELISA, IHC, IF, DB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Titration of the SMAD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the SMAD4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- SMAD4 (SMAD Family Member 4 (SMAD4))
- Andere Bezeichnung
- SMAD4 (SMAD4 Produkte)
- Synonyme
- smad4 antikoerper, DPC4 antikoerper, JIP antikoerper, MADH4 antikoerper, MYHRS antikoerper, AW743858 antikoerper, D18Wsu70e antikoerper, Madh4 antikoerper, XSmad4alpha antikoerper, Xsmad4 antikoerper, dpc4 antikoerper, jip antikoerper, madh4 antikoerper, xsmad4a antikoerper, SMAD family member 4 antikoerper, Smad4 protein antikoerper, SMAD family member 4, gene 1 L homeolog antikoerper, SMAD4 antikoerper, smad4 antikoerper, Smad4 antikoerper, smad4.1.L antikoerper
- Hintergrund
- In muscle physiology, SMAD4 plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8. Acts synergistically with SMAD1 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to SMAD binding elements (SBEs) (5'-GTCT/AGAC-3') within BMP response element (BMPRE) of cardiac activating regions (By similarity). [UniProt]
- UniProt
- Q13485
- Pathways
- Zellzyklus, Chromatin Binding, Autophagie
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