SMAD4 Antikörper (AA 400-428)
Kurzübersicht für SMAD4 Antikörper (AA 400-428) (ABIN3032608)
Target
Alle SMAD4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 400-428
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Verwendungszweck
- SMAD4 Antibody
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Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat, Bovine, Pig
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 400-428 from the human protein was used as the immunogen for this SMAD4 antibody.
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Isotyp
- Ig Fraction
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anti-SMAD Family Member 4 (SMAD4) (N-Term) antibody
SMAD4 Reaktivität: Human WB, IP, CUT&RUN Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 1-552) antibodySMAD4 Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 3E2 unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 255-284) antibodySMAD4 Reaktivität: Human, Maus WB, IF Wirt: Kaninchen Polyclonal RB14714 unconjugated
anti-SMAD Family Member 4 (SMAD4) antibodySMAD4 Reaktivität: Human, Maus WB, IHC, ELISA, ICC, FACS Wirt: Maus Monoclonal 4G1C6 unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 27-195) antibodySMAD4 Reaktivität: Human WB, IHC, ELISA, IP Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) antibodyKD Validated SMAD4 Reaktivität: Human WB, FACS, IF (p) Wirt: Kaninchen Monoclonal 23GB975 unconjugated Recombinant Antibody
anti-SMAD Family Member 4 (SMAD4) (AA 400-428), (C-Term) antibodySMAD4 Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB20720 unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 40-120) antibodySMAD4 Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (pThr277) antibodySMAD4 Reaktivität: Human IHC, ELISA, IF, DB Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) antibodySMAD4 Reaktivität: Human, Maus, Ratte WB, IHC (p), IF (cc) Wirt: Kaninchen Monoclonal 3A1 unconjugated
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Applikationshinweise
- Titration of the SMAD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Aliquot the SMAD4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SMAD4 (SMAD Family Member 4 (SMAD4))
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Andere Bezeichnung
- SMAD4
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Hintergrund
- In muscle physiology, SMAD4 plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8. Acts synergistically with SMAD1 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to SMAD binding elements (SBEs) (5'-GTCT/AGAC-3') within BMP response element (BMPRE) of cardiac activating regions (By similarity). [UniProt]
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UniProt
- Q13485
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Pathways
- Zellzyklus, Chromatin Binding, Autophagie
Target
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