ATG14 Antikörper
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- Target Alle ATG14 Antikörper anzeigen
- ATG14 (ATG14 Autophagy Related 14 (ATG14))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ATG14 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Spezifität
- At least three isoforms of ATG14 are known to exist, this antibody will detect all three isoforms
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- ATG14 antibody was raised against an 18 amino acid synthetic peptide near the center of human ATG14.
- Isotyp
- IgG
- Top Product
- Discover our top product ATG14 Primärantikörper
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- Applikationshinweise
- ATG14 antibody can be used for detection of ATG14 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
- Kommentare
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(IN) Autophagy-related 14
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- ATG14 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Haltbarkeit
- 12 months
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- Target
- ATG14 (ATG14 Autophagy Related 14 (ATG14))
- Andere Bezeichnung
- ATG14 (ATG14 Produkte)
- Synonyme
- ATG14L antikoerper, BARKOR antikoerper, KIAA0831 antikoerper, 4832427M01 antikoerper, Atg14L antikoerper, D14Ertd114e antikoerper, D14Ertd436e antikoerper, RGD1304610 antikoerper, autophagy related 14 antikoerper, ATG14 antikoerper, Atg14 antikoerper
- Hintergrund
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Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG14 is a subunit of a class III phosphatidylinositol (PtdIns) 3-kinase complex that targets the complex to the endoplasmic reticulum, the site of autophagosome formation.
Synonyms: Autophagy-related 14, ATG14L, beclin1-associated autophagy-related key regulator, beclin 1-interacting protein, BARKOR - Molekulargewicht
- 54 kDa
- Gen-ID
- 22863
- NCBI Accession
- NP_055739
- Pathways
- Autophagie
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