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ATG14 Antikörper

ATG14 Reaktivität: Human, Ratte WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN4950253
  • Target Alle ATG14 Antikörper anzeigen
    ATG14 (ATG14 Autophagy Related 14 (ATG14))
    Reaktivität
    • 46
    • 15
    • 7
    • 1
    Human, Ratte
    Wirt
    • 38
    • 8
    Kaninchen
    Klonalität
    • 38
    • 8
    Polyklonal
    Konjugat
    • 18
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser ATG14 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 22
    • 16
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    Antigen affinity
    Immunogen
    Amino acids RDRERFIDKKERLSRLKSKQEEFQKEVLKAME of human ATG14L were used as the immunogen for the ATG14L antibody.
    Isotyp
    IgG
    Top Product
    Discover our top product ATG14 Primärantikörper
  • Applikationshinweise
    Optimal dilution of the ATG14L antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    After reconstitution, the ATG14L antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    ATG14 (ATG14 Autophagy Related 14 (ATG14))
    Andere Bezeichnung
    ATG14L (ATG14 Produkte)
    Synonyme
    ATG14L antikoerper, BARKOR antikoerper, KIAA0831 antikoerper, 4832427M01 antikoerper, Atg14L antikoerper, D14Ertd114e antikoerper, D14Ertd436e antikoerper, RGD1304610 antikoerper, autophagy related 14 antikoerper, ATG14 antikoerper, Atg14 antikoerper
    Hintergrund
    ATG14 (also known as beclin-1-associated autophagy-related key regulator (Barkor) or ATG14L), an essential autophagy-specific regulator of the class III phosphatidylinositol 3-kinase complex, promotes membrane tethering of protein-free liposomes, and enhances hemifusion and full fusion of proteoliposomes reconstituted with the target (t)-SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) syntaxin 17 (STX17) and SNAP29, and the vesicle (v)-SNARE VAMP8 (vesicle-associated membrane protein 8). ATG14 binds to the SNARE core domain of STX17 through its coiled-coil domain, and stabilizes the STX17-SNAP29 binary t-SNARE complex on autophagosomes.
    UniProt
    Q6ZNE5
    Pathways
    Autophagie
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