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anti-Human WT1 Antikörper:
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Human Monoclonal WT1 Primary Antibody für IHC, IHC (fro) - ABIN258719
Rauscher, Morris, Fredericks, Lopez-Guisa, Balakrishnan, Jost, Herlyn, Rodeck: Characterization of monoclonal antibodies directed to the amino-terminus of the WT1, Wilms' tumor suppressor protein. in Hybridoma 1998
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Human Polyclonal WT1 Primary Antibody für CyTOF, FACS - ABIN4899232
Da Sacco, Lemley, Sedrakyan, Zanusso, Petrosyan, Peti-Peterdi, Burford, De Filippo, Perin: A novel source of cultured podocytes. in PLoS ONE 2013
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Human Polyclonal WT1 Primary Antibody für ELISA, WB - ABIN188555
Rao, Pham, Imam, MacLean, Murali, Furuta, Sinha-Hikim, Wilkinson: Tissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesis. in Genes & development 2006
Human Monoclonal WT1 Primary Antibody für FACS, IF - ABIN5590995
Rauscher: The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor suppressor. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993
This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.
Wilms tumor protein
, amino-terminal domain of EWS
, last three zinc fingers of the DNA-binding domain of WT1
, Chick Wilm's tumour protein
, Wilms tumor 1
, Wilms tumor protein homolog A
, Wilms tumor protein homolog
, Wilms tumor suppressor protein 1b
, Wilm's tumor suppressor
, Wilms tumor protein homolog B