anti-Ratte (Rattus) Phospholipase C gamma 2 Antikörper für Intracellular Staining

Recommended Phospholipase C gamma 2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Phospholipase C gamma 2 (PLCG2) Antikörper
  • PLCgamma2
  • Plcg-2
  • APLAID
  • FCAS3
  • phospholipase C, gamma 2
  • phospholipase C gamma 2
  • phospholipase C, gamma 2 (phosphatidylinositol-specific)
  • Plcg2
  • PLCG2
Epitop
pTyr759
49
49
40
18
15
6
5
5
5
5
4
4
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
341
178
168
12
4
4
4
4
3
1
Wirt
Maus
236
105
Klonalität
Monoklonal
Konjugat
Dieser Phospholipase C gamma 2 Antikörper ist konjugiert mit Alexa Fluor 488
9
8
8
8
8
5
5
5
5
5
5
5
5
5
5
3
3
3
3
3
3
3
3
3
3
3
3
1
1
Applikation
Intracellular Staining (ICS)
255
142
115
63
61
50
40
36
14
10
3
2
2
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN1177151
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1177149 ICS PE Mouse IgG1, kappa pTyr759 Anmelden zum Anzeigen K86-689-37 1
1 ABIN1177150 ICS Alexa Fluor 647 Mouse IgG1, kappa pTyr759 Anmelden zum Anzeigen K86-689-37 1

General

Antigen Phospholipase C gamma 2 (PLCG2) Antikörper
Epitop pTyr759
(49), (49), (40), (18), (15), (6), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(341), (178), (168), (12), (4), (4), (4), (4), (3), (1)
Wirt Maus
(236), (105)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser Phospholipase C gamma 2 Antikörper ist konjugiert mit Alexa Fluor 488
(9), (8), (8), (8), (8), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1)
Applikation Intracellular Staining (ICS)
(255), (142), (115), (63), (61), (50), (40), (36), (14), (10), (3), (2), (2), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Phospholipase C gamma 2 Antikörper

Target Details Phospholipase C gamma 2 Anwendungsinformationen Handhabung Bilder
Marke BD Phosflow™
Reinigung The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Phosphorylated Human PLC-gamma2 Peptide
Klon K86-689-37
Isotyp IgG1, kappa
Plasmids, Primers & others

Target Details Phospholipase C gamma 2

Produktdetails anti-Phospholipase C gamma 2 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung PLC-gamma 2 (PLCG2 Antibody Abstract)
Hintergrund The Phospholipase C (PLC) isozymes hydrolyze phosphatidyl inositol biphosphate to inositol triphosphate and diacylglycerol. The former causes release of calcium from the endoplasmic reticulum, while the latter is an activator of Protein Kinase C. Within the PLC family, PLC-gamma is the only member that contains SH2 and SH3 domains. These domains enable it to interact with protein tyrosine kinases and become enzymatically activated via phosphorylation. It exists as two isoforms: PLC-g1, which is ubiquitously expressed, and PLC-g2, which is found primarily in the hematopoietic system. PLC-g2-null mice exhibit impaired B lymphocyte maturation and defects in Fc receptor functions. Phosphorylation of PLC-g2 at tyrosines 753 and 759 (Y759) is required for activation of PLC-g2 enzyme activity. PLC-g2 phosphorylation at Y759 can be induced by stimulation of the B cell receptor in Ramos cells, the collagen receptor in platelets, and the T cell receptor in Jurkat cells, and it occurs downstream of Btk and BLNK in the signaling cascade of activated B cells. The K86-689.37.73 antibody recognizes PLC-g2 phosphorylated at Y759 in the SH2-SH3 linker region.
Pathways RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling

Anwendungsinformationen

Produktdetails anti-Phospholipase C gamma 2 Antikörper Target Details Phospholipase C gamma 2 Handhabung Bilder zurück nach oben
Probenmenge 20 μL
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Phospholipase C gamma 2 Antikörper Target Details Phospholipase C gamma 2 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Buffer Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The antibody was conjugated to Alexa Fluor® 488 under optimum conditions, and unreacted Alexa Fluor® 488 was removed.

Bilder

Produktdetails anti-Phospholipase C gamma 2 Antikörper Target Details Phospholipase C gamma 2 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Phospholipase C gamma 2 (PLCG2) (pTyr759) antibody (Alexa Fluor 488) (ABIN1177151) anti-Phospholipase C gamma 2 (PLCG2) (pTyr759) antibody (Alexa Fluor 488)