anti-Ratte (Rattus) Ephrin B2 Antikörper für Immunofluorescence

Recommended Ephrin B2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Ephrin B2 (EFNB2) Antikörper
  • EFNB2
  • efnb2
  • ephrin-B2
  • htkl
  • eplg5
  • htk-l
  • lerk5
  • ephrinB2
  • efnb2a
  • MGC68890
  • efnb2b
  • ELF-2
  • Epl5
  • Eplg5
  • Htk-L
  • LERK-5
  • Lerk5
  • NLERK-1
  • EPLG5
  • HTKL
  • LERK5
  • ephrin B2
  • ephrin-B2 precursor
  • ephrin B2 L homeolog
  • ephrin B2 S homeolog
  • EFNB2
  • efnb2
  • efnb2.L
  • efnb2.S
  • Efnb2
Epitop
AA 328-332
15
11
11
11
10
5
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
103
46
26
5
5
5
3
3
3
2
2
1
1
Wirt
Kaninchen
90
16
2
Klonalität
Polyklonal
Konjugat
Dieser Ephrin B2 Antikörper ist unkonjugiert
3
3
3
3
3
3
Applikation
Immunofluorescence (IF), Western Blotting (WB)
90
38
33
25
9
8
3
2
1
1
Hersteller
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Hersteller Produkt- Nr.
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Pubmed
3 Publikationen vorhanden

Bilder

image for anti-Ephrin B2 (EFNB2) (AA 328-332) antibody (ABIN197418)
image for anti-Ephrin B2 (EFNB2) (AA 328-332) antibody (ABIN197418)
Produktnummer ABIN197418
$ 368.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN362834 IF WB Rabbit IgG AA 328-332 Anmelden zum Anzeigen Polyclonal 4
1 ABIN2881211 IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN274041 IF WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0

General

Antigen Ephrin B2 (EFNB2) Antikörper
Epitop AA 328-332
(15), (11), (11), (11), (10), (5), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(103), (46), (26), (5), (5), (5), (3), (3), (3), (2), (2), (1), (1)
Wirt Kaninchen
(90), (16), (2)
Klonalität
Polyklonal
Konjugat Dieser Ephrin B2 Antikörper ist unkonjugiert
(3), (3), (3), (3), (3), (3)
Applikation Immunofluorescence (IF), Western Blotting (WB)
(90), (38), (33), (25), (9), (8), (3), (2), (1), (1)
Pubmed 3 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Ephrin B2 Antikörper

Target Details Ephrin B2 Anwendungsinformationen Handhabung Referenzen für anti-Ephrin B2 Antikörper (ABIN197418) Bilder
Spezifität This antibody AP02708PU detects endogenous levels of total Ephrin-B2 protein.
Reinigung Immunoaffinity Chromatography using epitope-specific immunogen.
Immunogen Peptide Sequence around amino acids 328~332 (N-I-Y-Y-K) derived from Human Ephrin-B2.

Target Details Ephrin B2

Produktdetails anti-Ephrin B2 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Ephrin B2 Antikörper (ABIN197418) Bilder zurück nach oben
Antigen
Andere Bezeichnung Ephrin-B2 (EFNB2 Antibody Abstract)
Hintergrund Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP)and also interacts with PRKCABP and GRIP1. This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. Ephrin-B2 also binds EphA4, EphB1, EphB2, EphB3 and EphB4. Ephrin-B2 can be detected on monocytes, mesangial cells, CD34+ stem cells, bone marrow fibroblasts, activated melanocytes and melanoma cells, and pre-artery endothelial cells.Synonyms: EFNB2, EPH-related receptor tyrosine kinase ligand 5, EPLG5, HTK ligand, HTK-L, HTKL, LERK-5, LERK5
Gen-ID 1948
NCBI Accession NP_004084
UniProt P52799
Pathways RTK Signalweg, Regulation of Muscle Cell Differentiation

Anwendungsinformationen

Produktdetails anti-Ephrin B2 Antikörper Target Details Ephrin B2 Handhabung Referenzen für anti-Ephrin B2 Antikörper (ABIN197418) Bilder zurück nach oben
Applikationshinweise Western blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Ephrin B2 Antikörper Target Details Ephrin B2 Anwendungsinformationen Referenzen für anti-Ephrin B2 Antikörper (ABIN197418) Bilder zurück nach oben
Format Liquid
Konzentration 1.0 mg/mL
Buffer PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung -20 °C
Informationen zur Lagerung Store the antibody (in aliquots) at -20 °C.

Referenzen für anti-Ephrin B2 Antikörper (ABIN197418)

Produktdetails anti-Ephrin B2 Antikörper Target Details Ephrin B2 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Chrencik, Brooun, Kraus, Recht, Kolatkar, Han, Seifert, Widmer, Auer, Kuhn: "Structural and biophysical characterization of the EphB4*ephrinB2 protein-protein interaction and receptor specificity." in: The Journal of biological chemistry, Vol. 281, Issue 38, pp. 28185-92, 2006

Kertesz, Krasnoperov, Reddy, Leshanski, Kumar, Zozulya, Gill: "The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth." in: Blood, Vol. 107, Issue 6, pp. 2330-8, 2006

Noren, Lu, Freeman, Koolpe, Pasquale: "Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 15, pp. 5583-8, 2004

Bilder

Produktdetails anti-Ephrin B2 Antikörper Target Details Ephrin B2 Anwendungsinformationen Handhabung Referenzen für anti-Ephrin B2 Antikörper (ABIN197418) zurück nach oben
Bilder des Herstellers
image for anti-Ephrin B2 (EFNB2) (AA 328-332) antibody (ABIN197418) anti-Ephrin B2 (EFNB2) (AA 328-332) antibody
image for anti-Ephrin B2 (EFNB2) (AA 328-332) antibody (ABIN197418) anti-Ephrin B2 (EFNB2) (AA 328-332) antibody (Image 2)