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Produktnummer ABIN6261455
  • Target Alle Ephrin B2 (EFNB2) Antikörper anzeigen
    Ephrin B2 (EFNB2)
    Bindungsspezifität
    • 10
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 57
    • 34
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 52
    • 4
    • 1
    Kaninchen
    Klonalität
    • 44
    • 12
    Polyklonal
    Konjugat
    • 34
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Dieser Ephrin B2 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 19
    • 13
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Ephrin B2 Antibody detects endogenous levels of total Ephrin B2.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human Ephrin B2, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    Ephrin B2 (EFNB2)
    Andere Bezeichnung
    EFNB2 (EFNB2 Produkte)
    Synonyme
    EFNB2 antikoerper, efnb2 antikoerper, ephrin-B2 antikoerper, htkl antikoerper, eplg5 antikoerper, htk-l antikoerper, lerk5 antikoerper, ephrinB2 antikoerper, efnb2a antikoerper, MGC68890 antikoerper, efnb2b antikoerper, ELF-2 antikoerper, Epl5 antikoerper, Eplg5 antikoerper, Htk-L antikoerper, LERK-5 antikoerper, Lerk5 antikoerper, NLERK-1 antikoerper, EPLG5 antikoerper, HTKL antikoerper, LERK5 antikoerper, ephrin B2 antikoerper, ephrin-B2 precursor antikoerper, ephrin B2 L homeolog antikoerper, ephrin B2 S homeolog antikoerper, EFNB2 antikoerper, efnb2 antikoerper, efnb2.L antikoerper, efnb2.S antikoerper, Efnb2 antikoerper
    Hintergrund

    Description: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.

    Gene: EFNB2

    Molekulargewicht
    36kDa
    Gen-ID
    1948
    UniProt
    P52799
    Pathways
    RTK Signalweg, Regulation of Muscle Cell Differentiation
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