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IL1RN Protein (AA 26-177)

IL1RN Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >90 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7504980
  • Target Alle IL1RN Proteine anzeigen
    IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 26-177
    Spezies
    • 18
    • 10
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 33
    • 8
    • 5
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequenz
    Arg26-Glu177
    Produktmerkmale
    A DNA sequence encoding the Human IL-1Ra Protein(P18510)(Arg26-Glu177)was expressed with a polyhistidine tag at the N-terminus.
    Reinheit
    >90 % as determined by reducing SDS-PAGE.
    Top Product
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  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    12 months
  • Target
    IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
    Andere Bezeichnung
    IL-1Ra (IL1RN Produkte)
    Synonyme
    DIRA Protein, ICIL-1RA Protein, IL-1RN Protein, IL-1ra Protein, IL-1ra3 Protein, IL1F3 Protein, IL1RA Protein, IRAP Protein, MVCD4 Protein, IRAP1 Protein, IL1RN Protein, IL-1RA Protein, F630041P17Rik Protein, interleukin 1 receptor antagonist Protein, interleukin 1 receptor antagonist-like Protein, IL1RN Protein, Il1rn Protein, IL1RNL Protein
    Hintergrund

    Background: Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2, however, the physiological relevance of the latter association is unsure.

    Synonym: Interleukin-1 receptor antagonist protein,IL-1RN,IL-1ra,IRAP,ICIL-1RA,IL1 inhibitor,Anakinra,IL1RN,IL1F3,IL1RA

    Molekulargewicht
    19.4 kDa
    UniProt
    P18510
    Pathways
    NF-kappaB Signalweg, Hormone Transport, Cancer Immune Checkpoints
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