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CNTF Protein

CNTF Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7455693
  • Target Alle CNTF Proteine anzeigen
    CNTF (Ciliary Neurotrophic Factor (CNTF))
    Protein-Typ
    Recombinant
    Spezies
    • 16
    • 9
    • 3
    • 2
    • 2
    • 2
    Human
    Quelle
    • 25
    • 3
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Verwendungszweck
    Recombinant Human Ciliary Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding Ala2-Met200 is expressed.
    Produktmerkmale
    Extracellular Domain Protein
    Reinheit
    Greater than 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CNTF Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, pH 8.0.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    12 months
  • Target
    CNTF (Ciliary Neurotrophic Factor (CNTF))
    Andere Bezeichnung
    CNTF (CNTF Produkte)
    Synonyme
    GPA Protein, CNTF Protein, HCNTF Protein, AI429687 Protein, ciliary neurotrophic factor Protein, CNTF Protein, Cntf Protein
    Hintergrund
    Ciliary Neurotrophic Factor, CNTFCiliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83 % homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-derived endothelial cell growth factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown.
    Molekulargewicht
    22.93 KDa
    UniProt
    P26441
    Pathways
    JAK-STAT Signalweg
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