CNTF Protein
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- Target Alle CNTF Proteine anzeigen
- CNTF (Ciliary Neurotrophic Factor (CNTF))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Verwendungszweck
- Recombinant Human Ciliary Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding Ala2-Met200 is expressed.
- Produktmerkmale
- Extracellular Domain Protein
- Reinheit
- Greater than 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CNTF Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, pH 8.0.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Haltbarkeit
- 12 months
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- Target
- CNTF (Ciliary Neurotrophic Factor (CNTF))
- Andere Bezeichnung
- CNTF (CNTF Produkte)
- Synonyme
- GPA Protein, CNTF Protein, HCNTF Protein, AI429687 Protein, ciliary neurotrophic factor Protein, CNTF Protein, Cntf Protein
- Hintergrund
- Ciliary Neurotrophic Factor, CNTFCiliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83 % homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-derived endothelial cell growth factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown.
- Molekulargewicht
- 22.93 KDa
- UniProt
- P26441
- Pathways
- JAK-STAT Signalweg
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