ULBP2 Protein (AA 26-216) (Fc Tag)
-
- Target Alle ULBP2 Proteine anzeigen
- ULBP2 (UL16 Binding Protein 2 (ULBP2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 26-216
- Spezies
- Human
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses ULBP2 Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Human ULBP-2 Protein
- Sequenz
- Gly26-Ser216
- Produktmerkmale
- Recombinant Human ULBP-2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gly26-Ser216.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human NKG2D, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human ULBP-2, hFc Tag with the EC50 of 94.7ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product ULBP2 Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- ULBP2 (UL16 Binding Protein 2 (ULBP2))
- Andere Bezeichnung
- ULBP-2 (ULBP2 Produkte)
- Synonyme
- N2DL2 Protein, RAET1H Protein, UL16 binding protein 2 Protein, NKG2D ligand 2-like Protein, ULBP2 Protein, LOC100355436 Protein
- Hintergrund
- ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.
- Molekulargewicht
- 48.40 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9BZM5
-