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ULBP2 Protein (Fc Tag)

ULBP2 Spezies: Human Wirt: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Produktnummer ABIN7318835
  • Target Alle ULBP2 Proteine anzeigen
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    Human
    Quelle
    • 7
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses ULBP2 Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Human ULBP2/N2DL-2 Protein (Fc Tag)(Active)
    Sequenz
    Gly26-Ser217
    Produktmerkmale
    Recombinant Human UL16 Binding Protein-2/NKG2D ligand 2 is produced by our Mammalian expression system and the target gene encoding Gly26-Ser217 is expressed with a Fc tag at the C-terminus.
    Reinheit
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Immobilized Human NKG2DL2-Fc at 8μg/ml(100 μl/well) can bind Human NKG2D-His(Cat: PKSH033409). The ED50 of Human NKG2DL2-Fc is 10.32 ug/ml .
    Top Product
    Discover our top product ULBP2 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    Andere Bezeichnung
    ULBP2/N2DL-2 (ULBP2 Produkte)
    Synonyme
    N2DL2 Protein, RAET1H Protein, UL16 binding protein 2 Protein, NKG2D ligand 2-like Protein, ULBP2 Protein, LOC100355436 Protein
    Hintergrund

    Background: NKG2D Ligand 2 (N2DL2) is a member of a family of cell-surface proteins. N2DL2 function as ligands for human cytomegalovirus glycoprotein UL16. N2DL2 is anchored to the membrane via a GPI-linkage. N2DL2 is bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, T cells. Engagement of NKG2D results in the activation of cytolytic activity and cytokine production by these effects cells. The ULBPs are expressed on some tumor cells and have been implicated in tumor surveillance.

    Synonym: NKG2D Ligand 2, N2DL-2, NKG2DL2, ALCAN-Alpha, Retinoic Acid Early Transcript 1H, UL16-Binding Protein 2, ULBP2, N2DL2, RAET1H

    Molekulargewicht
    51.4 kDa
    UniProt
    Q9BZM5
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