ULBP2 Protein (AA 26-217) (His tag)

Produktnummer ABIN1097760

Produktdetails

Target: ULBP2 (UL16 Binding Protein 2 (ULBP2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 26-217

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses ULBP2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-6His)

Sequenz: GRADPHSLCY DITVIPKFRP GPRWCAVQGQ VDEKTFLHYD CGNKTVTPVS PLGKKLNVTT AWKAQNPVLR EVVDILTEQL RDIQLENYTP KEPLTLQARM SCEQKAEGHS SGSWQFSFDG QIFLLFDSEK RMWTTVHPGA RKMKEKWEND KVVAMSFHYF SMGDCIGWLE DFLMGMDSTL EPSAGAPLAM SSVDHHHHHH

Produktmerkmale:

Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-6His)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: ULBP2 (UL16 Binding Protein 2 (ULBP2))

Andere Bezeichnung: NKG2D Ligand 2/N2DL2 (ULBP2 Produkte)

Synonyme: N2DL2 Protein, RAET1H Protein, UL16 binding protein 2 Protein, NKG2D ligand 2-like Protein, ULBP2 Protein, LOC100355436 Protein

Hintergrund: Recombinant Human NKG2D Ligand 2/N2DL2 produced by transfected human cells is a secreted protein with sequence (Gly26-Ser216) of Human N2DL2 fused with a polyhistidine tag at the C-terminus.
NKG2D Ligand 2 (N2DL2) is a member of a family of cell-surface proteins. N2DL2 function as ligands for human cytomegalovirus glycoprotein UL16. N2DL2 is anchored to the membrane via a GPI-linkage. N2DL2 is bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, T cells. Engagement of NKG2D results in the activation of cytolytic activity and cytokine production by these effects cells. The ULBPs are expressed on some tumor cells and have been implicated in tumor surveillance.

Molekulargewicht: 22.78 kDa

UniProt: Q9BZM5