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ULBP2 Protein (AA 26-217) (His-Avi Tag)

ULBP2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7275815
  • Target Alle ULBP2 Proteine anzeigen
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 26-217
    Spezies
    Human
    Quelle
    • 6
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses ULBP2 Protein ist gelabelt mit His-Avi Tag.
    Verwendungszweck
    Human ULBP-2 Protein
    Sequenz
    Gly26-Ser217
    Produktmerkmale
    Recombinant Human ULBP-2 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly26-Ser217.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human ULBP-2, His Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.26μg/ml determined by ELISA. See testing image for detail.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    Andere Bezeichnung
    ULBP-2 (ULBP2 Produkte)
    Synonyme
    N2DL2 Protein, RAET1H Protein, UL16 binding protein 2 Protein, NKG2D ligand 2-like Protein, ULBP2 Protein, LOC100355436 Protein
    Hintergrund
    ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.
    Molekulargewicht
    24.6 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
    UniProt
    Q9BZM5
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