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TLR3 Protein (AA 23-703) (His tag,Biotin)

TLR3 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7275747
  • Target Alle TLR3 Proteine anzeigen
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 23-703
    Spezies
    • 11
    • 9
    • 2
    • 1
    Human
    Quelle
    • 8
    • 7
    • 4
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses TLR3 Protein ist gelabelt mit His tag,Biotin.
    Verwendungszweck
    Biotinylated Human TLR3 Protein (Primary Amine Labeling)
    Sequenz
    Ser23-Glu703
    Produktmerkmale
    Recombinant Biotinylated Human TLR3 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus.It contains Ser23-Glu703.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product TLR3 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Andere Bezeichnung
    TLR3 (TLR3 Produkte)
    Synonyme
    CD283 Protein, IIAE2 Protein, AI957183 Protein, zgc:123006 Protein, toll like receptor 3 Protein, toll-like receptor 3 Protein, TLR3 Protein, Tlr3 Protein, tlr3 Protein
    Hintergrund
    TLR3 is expressed in the central nervous system (CNS), where it is required to control HSV-1, which spreads from the epithelium to the CNS via cranial nerves. TLR3 is also expressed in epithelial and dendritic cells, which apparently use TLR3-independent pathways to prevent further dissemination of HSV-1 and to provide resistance to other pathogens in TLR3-deficient patients. Human TLR3 appears to be redundant in host defense to most microbes but is vital for natural immunity to HSV-1 in the CNS, which suggests that neurotropic viruses have contributed to the evolutionary maintenance of TLR3.
    Molekulargewicht
    78.7 kDa. Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result.
    UniProt
    Q6PCD4
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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