TLR3 Protein (AA 31-711) (His tag)
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- Target Alle TLR3 Proteine anzeigen
- TLR3 (Toll-Like Receptor 3 (TLR3))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 31-711
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Spezies
- Cynomolgus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses TLR3 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Cynomolgus TLR3 Protein
- Sequenz
- Ser31-Glu711
- Produktmerkmale
- Recombinant Cynomolgus TLR3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser31-Glu711.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product TLR3 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- TLR3 (Toll-Like Receptor 3 (TLR3))
- Andere Bezeichnung
- TLR3 (TLR3 Produkte)
- Synonyme
- CD283 Protein, IIAE2 Protein, AI957183 Protein, zgc:123006 Protein, toll like receptor 3 Protein, toll-like receptor 3 Protein, TLR3 Protein, Tlr3 Protein, tlr3 Protein
- Hintergrund
- TLR3 is expressed in the central nervous system (CNS), where it is required to control HSV-1, which spreads from the epithelium to the CNS via cranial nerves. TLR3 is also expressed in epithelial and dendritic cells, which apparently use TLR3-independent pathways to prevent further dissemination of HSV-1 and to provide resistance to other pathogens in TLR3-deficient patients. Human TLR3 appears to be redundant in host defense to most microbes but is vital for natural immunity to HSV-1 in the CNS, which suggests that neurotropic viruses have contributed to the evolutionary maintenance of TLR3.
- Molekulargewicht
- 78.04 kDa. Due to glycosylation, the protein migrates to 95-115 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A2K5WT39
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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