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Oncostatin M Protein (OSM) (His-Avi Tag,Biotin)

OSM Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Produktnummer ABIN7275380
  • Target Alle Oncostatin M (OSM) Proteine anzeigen
    Oncostatin M (OSM)
    Protein-Typ
    Recombinant
    Spezies
    • 25
    • 7
    • 4
    • 3
    • 1
    • 1
    Human
    Quelle
    • 22
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Oncostatin M Protein ist gelabelt mit His-Avi Tag,Biotin.
    Sequenz
    Ala26-Arg221
    Reinheit
    > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product OSM Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Oncostatin M (OSM)
    Andere Bezeichnung
    Oncostatin M (OSM Produkte)
    Synonyme
    OSM Protein, OncoM Protein, oncostatin M Protein, OSM Protein, Osm Protein
    Hintergrund
    Oncostatin M, OSM, MGC20461,OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
    Molekulargewicht
    25.1 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
    UniProt
    P13725
    Pathways
    JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
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