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Oncostatin M Protein (OSM) (AA 26-234) (His tag)

OSM Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Produktnummer ABIN667495
  • Target Alle Oncostatin M (OSM) Proteine anzeigen
    Oncostatin M (OSM)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 26-234
    Spezies
    • 25
    • 7
    • 4
    • 3
    • 1
    • 1
    Human
    Quelle
    • 21
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses Oncostatin M Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    OSM, 26-234aa, Human, His tag, E.coli
    Reinheit
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product OSM Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
    Lagerung
    4 °C
  • Target
    Oncostatin M (OSM)
    Andere Bezeichnung
    OSM (OSM Produkte)
    Synonyme
    OSM Protein, OncoM Protein, oncostatin M Protein, OSM Protein, Osm Protein
    Hintergrund
    OSM, also known as Oncostatin M, is a pleiotropic cytokine that belongs to the interleukin 6 group of cytokines. Of these cytokines it most closely resembles leukemia inhibitory factor (LIF) in both structure and function. However, it is as yet poorly defined and is proving important in liver development, haematopoeisis, inflammation and possibly CNS development. It is also associated with bone formation and destruction. OSM signals through cell surface receptors that contain the protein gp130. The type I receptor is composed of gp130 and LIFR, the type II receptor is composed of gp130 and OSMR. Recombinant human OSM protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Oncostatin M, MGC20461, Oncostatin M precursor. NCBI no.: NP_065391
    Molekulargewicht
    25.9 kDa (230aa), confirmed by MALDI-TOF
    Pathways
    JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
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