Oncostatin M Protein (OSM) (AA 26-221) (His-Avi Tag)
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- Target Alle Oncostatin M (OSM) Proteine anzeigen
- Oncostatin M (OSM)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 26-221
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Oncostatin M Protein ist gelabelt mit His-Avi Tag.
- Verwendungszweck
- Human Oncostatin M/OSM Protein
- Sequenz
- Ala26-Arg221
- Produktmerkmale
- Recombinant Human Oncostatin M/OSM Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala26-Arg221.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.662 μM as determined in SPR assay (Biacore T200). See testing image for detail.
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Oncostatin M (OSM) (Active) protein
OSM Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Oncostatin M (OSM) (AA 25-206) protein (His tag)OSM Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oncostatin M (OSM) protein (His-Avi Tag,Biotin)OSM Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Oncostatin M (OSM) (AA 26-239) protein (His tag)OSM Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Oncostatin M (OSM) (AA 26-221) protein (His tag)OSM Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Oncostatin M (OSM) (AA 26-234) protein (His tag)OSM Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Oncostatin M (OSM) (AA 1-252) protein (GST tag)OSM Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Oncostatin M (OSM) (AA 25-206) protein (His tag)Crystallography grade OSM Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Oncostatin M (OSM) (AA 26-221) protein (His tag)Crystallography grade OSM Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Oncostatin M (OSM)
- Andere Bezeichnung
- OSM (OSM Produkte)
- Synonyme
- OSM Protein, OncoM Protein, oncostatin M Protein, OSM Protein, Osm Protein
- Hintergrund
- OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
- Molekulargewicht
- 25.1 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
- UniProt
- P13725
- Pathways
- JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
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