CLEC7A Protein (AA 71-244) (Fc Tag)

Produktnummer ABIN7274366

Produktdetails

Target: CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

Protein-Typ: Recombinant

Proteineigenschaft: AA 71-244

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CLEC7A Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Mouse CLEC7A Protein

Sequenz: Gly71-Leu244

Produktmerkmale: Recombinant Mouse CLEC7A Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Gly71-Leu244.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

Andere Bezeichnung: CLEC7A (CLEC7A Produkte)

Synonyme: CLEC7A Protein, BGR Protein, Clecsf12 Protein, beta-GR Protein, CANDF4 Protein, CLECSF12 Protein, DECTIN1 Protein, Clec7b Protein, RGD1565140 Protein, C-type lectin domain containing 7A Protein, C-type lectin domain family 7, member a Protein, CLEC7A Protein, Clec7a Protein

Hintergrund: Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin receptor (CLR). Dectin-1 signaling axis has been suggested to be targeted as an effective therapeutic strategy for cancers. Dectin-1 has also been elucidated ascetically in the heart, respiratory, intestinal, neurological and developmental disorders.

Molekulargewicht: 46.08 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.

UniProt: Q6QLQ4

Pathways: Activation of Innate immune Response