CLEC7A Protein (AA 72-244) (Fc Tag)
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- Target Alle CLEC7A Proteine anzeigen
- CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 72-244
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Spezies
- Maus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CLEC7A Protein ist gelabelt mit Fc Tag.
- Applikation
- SDS-PAGE (SDS)
- Kreuzreaktivität
- Maus
- Produktmerkmale
- Mouse dectin-1 (aa 72-244) is fused at the C-terminus to the Fc portion of human IgG1.
- Reinheit
- >95 % (SDS-PAGE)
- Endotoxin-Niveau
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product CLEC7A Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with 50 μL sterile water.
- Konzentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Haltbarkeit
- 6 months
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- Target
- CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
- Andere Bezeichnung
- Dectin-1 (CLEC7A Produkte)
- Synonyme
- CLEC7A Protein, BGR Protein, Clecsf12 Protein, beta-GR Protein, CANDF4 Protein, CLECSF12 Protein, DECTIN1 Protein, Clec7b Protein, RGD1565140 Protein, C-type lectin domain containing 7A Protein, C-type lectin domain family 7, member a Protein, CLEC7A Protein, Clec7a Protein
- Hintergrund
- Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognizes beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognizes alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain.
- Molekulargewicht
- ~56kDa (SDS-PAGE)
- UniProt
- Q6QLQ4
- Pathways
- Activation of Innate immune Response
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