Amphiregulin Protein (AREG) (AA 101-187) (Fc Tag)
-
- Target Alle Amphiregulin (AREG) Proteine anzeigen
- Amphiregulin (AREG)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 101-187
-
Spezies
- Human
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Amphiregulin Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Human AREG Protein
- Sequenz
- Ser101-Lys187
- Produktmerkmale
- Recombinant Human AREG Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ser101-Lys187.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human AREG, hFc Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-AREG Antibody, hFc Tag with the EC50 of 21.5ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product AREG Protein
-
Amphiregulin (AREG) (Active) protein
AREG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Amphiregulin (AREG) (AA 100-248) protein (Fc Tag)AREG Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Amphiregulin (AREG) (AA 101-198) protein (His tag)AREG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Amphiregulin (AREG) (AA 101-198) protein (His-IF2DI Tag)AREG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Amphiregulin (AREG) (AA 1-252) protein (GST tag)AREG Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Amphiregulin (AREG) (AA 20-129) protein (GST tag)AREG Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- Amphiregulin (AREG)
- Andere Bezeichnung
- AREG (AREG Produkte)
- Synonyme
- AR Protein, CRDGF Protein, SDGF Protein, Sdgf Protein, AREG Protein, AREGB Protein, AREG/SDGF Protein, amphiregulin Protein, AREG Protein, Areg Protein
- Hintergrund
- Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decreased by AREG silencing in an orthotopic model of pancreatic cancer. AREG may play a critical role in cell migration, invasion, and EMT by activating the EGFR/ERK/NF-κB signalling pathway in pancreatic cancer cells.
- Molekulargewicht
- 37.3 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Tris-Bis PAGE result.
- UniProt
- P15514
- Pathways
- RTK Signalweg, EGFR Signaling Pathway
-
