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Amphiregulin Protein (AREG) (AA 101-198)

AREG Spezies: Human Wirt: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Produktnummer ABIN2017667
  • Target Alle Amphiregulin (AREG) Proteine anzeigen
    Amphiregulin (AREG)
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 101-198
    Spezies
    • 10
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Quelle
    • 18
    • 2
    • 2
    • 2
    HEK-293T Cells
    Produktmerkmale
    ED50 < 0.2 ng/mL, measured in a cell proliferation assay using 3T3 cells.
    Reinheit
    > 95 % as analyzed by SDS-PAGE.
    Endotoxin-Niveau
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product AREG Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Lyophilized recombinant Human Amphiregulin remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Amphiregulin should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Haltbarkeit
    6 months
  • Target
    Amphiregulin (AREG)
    Andere Bezeichnung
    Amphiregulin (AREG Produkte)
    Synonyme
    AR Protein, CRDGF Protein, SDGF Protein, Sdgf Protein, AREG Protein, AREGB Protein, AREG/SDGF Protein, amphiregulin Protein, AREG Protein, Areg Protein
    Hintergrund
    Amphiregulin is a member of the EGF family of cytokines, which comprises at least ten proteins including EGF, TGF-alpha, HB-EGF, Epiregulin, Tomoregulin, Neuregulins and the various heregulins. Through the EGF/TGF-alpha receptor, it stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin's extracellular domain is proteolytically processed to release the mature protein.
    Synonyms: AR, AREG, Colorectum cell-derived growth factor (CRDGF)
    Molekulargewicht
    15-20 kDa, observed by reducing SDS-PAGE.
    UniProt
    Q5U026
    Pathways
    RTK Signalweg, EGFR Signaling Pathway
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