Clusterin Protein (CLU) (His tag,Fc Tag)

Produktnummer ABIN7318318

Produktdetails

Target: Clusterin (CLU)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Clusterin Protein ist gelabelt mit His tag,Fc Tag.

Verwendungszweck: Recombinant Human Clusterin/ApoJ Protein (Fc & His Tag)

Sequenz: Asp23-Glu449

Produktmerkmale: Recombinant Human Clusterin is produced by our Mammalian expression system and the target gene encoding Asp23-Glu449 is expressed with a Fc, 6His tag at the C-terminus.

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Clusterin (CLU)

Andere Bezeichnung: Clusterin/ApoJ (CLU Produkte)

Synonyme: LOC100136120 Protein, clu Protein, MGC53055 Protein, zgc:73352 Protein, xclu Protein, MGC89163 Protein, CLU Protein, APO-J Protein, APOJ Protein, CLI Protein, CLU1 Protein, CLU2 Protein, KUB1 Protein, NA1/NA2 Protein, SGP-2 Protein, SGP2 Protein, SP-40 Protein, TRPM-2 Protein, TRPM2 Protein, DAG Protein, RATTRPM2B Protein, SP40 Protein, TRPM2B Protein, Trpm2 Protein, Trpmb Protein, AI893575 Protein, ApoJ Protein, Cli Protein, D14Ucla3 Protein, Sgp-2 Protein, Sgp2 Protein, Sugp-2 Protein, GP80 Protein, gpIII Protein, 40 Protein, clusterin-1 Protein, clusterin L homeolog Protein, clusterin Protein, Clusterin Protein, LOC100136120 Protein, clu.L Protein, clu Protein, CLU Protein, clus Protein, Clu Protein, LOC101113728 Protein

Hintergrund:

Background: Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain and liver. Clusterin has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. In addition,Clusterin is up/ down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity and others.

Synonym: Clusterin, Aging-Associated Gene 4 Protein, Apolipoprotein J, Apo-J, Complement Cytolysis Inhibitor, CLI, Complement-Associated Protein SP-40, Ku70-Binding Protein 1, NA1/NA2, Testosterone-Repressed Prostate Message 2, TRPM-2, CLU, APOJ, CLI, KUB1,AAG4,APO-J,CLU1,CLU2,NA1/NA2,SGP-2,SGP2,SP-40

Molekulargewicht: 78.0 kDa

UniProt: P10909

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling