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Clusterin Protein (CLU) (AA 22-448, Nuclear) (His tag)
CLU
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
>90 % (SDS-PAGE)
SDS
Produktnummer ABIN1344140
Produktdetails
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Target
Alle Clusterin (CLU) Proteine anzeigen
Clusterin (CLU)
Protein-Typ
Recombinant
Proteineigenschaft
Nuclear, AA 22-448
Spezies
Alle Spezies für Clusterin Proteine
Maus
Quelle
Alle Expressionssysteme für Clusterin Proteine
Escherichia coli (E. coli)
Aufreinigungstag / Konjugat
Dieses Clusterin Protein ist gelabelt mit His tag.
Applikation
SDS-PAGE (SDS)
Kreuzreaktivität
Maus
Produktmerkmale
Mouse nuclear clusterin (aa 22-448) is fused at the C-terminus to a His-tag.
Reinheit
>90 % (SDS-PAGE)
Sterilität
0.2 μm filtered
Endotoxin-Niveau
<1EU/μg purified protein (LAL test, Lonza).
Top Product
Discover our top product CLU Protein
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
Lot specific
Buffer
0.2μm-filtered solution in 55 mM TRIS-Cl, pH 8.2, containing 150 mM NaCl.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Short Term Storage: +4°C Long Term Storage: -20°C Working aliquots are stable for up to 3 months when stored at -20°C.
Haltbarkeit
3 months
Antigendetails
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Target
Clusterin (CLU)
Andere Bezeichnung
Clusterin (CLU Produkte )
Synonyme
LOC100136120 Protein, clu Protein, MGC53055 Protein, zgc:73352 Protein, xclu Protein, MGC89163 Protein, CLU Protein, APO-J Protein, APOJ Protein, CLI Protein, CLU1 Protein, CLU2 Protein, KUB1 Protein, NA1/NA2 Protein, SGP-2 Protein, SGP2 Protein, SP-40 Protein, TRPM-2 Protein, TRPM2 Protein, DAG Protein, RATTRPM2B Protein, SP40 Protein, TRPM2B Protein, Trpm2 Protein, Trpmb Protein, AI893575 Protein, ApoJ Protein, Cli Protein, D14Ucla3 Protein, Sgp-2 Protein, Sgp2 Protein, Sugp-2 Protein, GP80 Protein, gpIII Protein, 40 Protein, clusterin-1 Protein, clusterin L homeolog Protein, clusterin Protein, Clusterin Protein, LOC100136120 Protein, clu.L Protein, clu Protein, CLU Protein, clus Protein, Clu Protein, LOC101113728 Protein
Hintergrund
Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80- kDa disulfide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling, and immune system regulation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.
Molekulargewicht
~45kDa (SDS-PAGE)
UniProt
Q549A5
Pathways
Apoptose , Negative Regulation of intrinsic apoptotic Signaling
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