BAX Protein (His tag)
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- Target Alle BAX Proteine anzeigen
- BAX (BCL2-Associated X Protein (BAX))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses BAX Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human BAX/BCL2L4 Protein (His Tag)
- Sequenz
- Met 1-Gln171
- Produktmerkmale
- Recombinant Human BCL2-associated X protein is produced by our E.coli expression system and the target gene encoding Met1-Gln171 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product BAX Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,2 mM EDTA,5 % Threhalose,30 % Glycerol, pH 7.4.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- BAX (BCL2-Associated X Protein (BAX))
- Andere Bezeichnung
- BAX/BCL2L4 (BAX Produkte)
- Synonyme
- BAX-ALPHA Protein, bax-A Protein, xBax Protein, xlbax Protein, BAX Protein, bax Protein, fj16e01 Protein, wu:fc50b10 Protein, wu:fj16e01 Protein, BCL2L4 Protein, zgc:112983 Protein, BCL2 associated X, apoptosis regulator Protein, BCL2-associated X protein L homeolog Protein, BCL2-associated X protein Protein, bcl2-associated X protein, a Protein, bcl2-associated X protein, b Protein, BAX Protein, bax.L Protein, bax Protein, baxa Protein, Bax Protein, baxb Protein
- Hintergrund
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Background: Apoptosis Regulator BAX (BAX) belongs to the Bcl-2 family. BAX exists as a homodimer and is expressed in a wide variety of tissues. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa). Although both isoforms contain BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. BAX accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. BAX also promotes activation of CASP3, and thereby apoptosis.
Synonym: Apoptosis Regulator BAX, Bcl-2-Like Protein 4, Bcl2-L-4, BAX, BCL2L4
- Molekulargewicht
- 22.1 kDa
- UniProt
- Q07812
- Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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