ATG10 Protein (T7 tag,His tag)

Produktnummer ABIN7318183

Dieses Recombinant ATG10-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für ATG10 Protein (T7 tag,His tag) (ABIN7318183)

Target: ATG10 (Autophagy Related 10 (ATG10))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses ATG10 Protein ist gelabelt mit T7 tag,His tag.

Verwendungszweck: Recombinant Human ATG10 Protein (His&T7 Tag)

Sequenz: Met 1-Thr190

Produktmerkmale: Recombinant Human Autophagy Related 10 Homolog is produced by our E.coli expression system and the target gene encoding Met1-Thr190 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 8.0.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: ATG10 (Autophagy Related 10 (ATG10))

Andere Bezeichnung: ATG10

Hintergrund:

Background: Ubiquitin-Like-Conjugating Enzyme ATG10 (ATG10) is a ubiquitous 28 kDa member of the ATG10 family protein. ATG10 acts as an E2-like enzyme, catalyzes the transfer of ATG12 to ATG5 during in the initial stages of autophagesome formation. The heterodimer of ATG5 and ATG12 subsequntly associates non-covalently with an ATG16 multimer to generate an antophagosome. ATG10 plays a role in the conjugation of ATG12 to ATG5 by interaction with MAP1LC3A. In addition, ATG10 can diretly interact with ATG5 or ATG7.

Synonym: Ubiquitin-Like-Conjugating Enzyme ATG10, Autophagy-Related Protein 10, APG10-Like, ATG10

Molekulargewicht: 24.5 kDa

UniProt: Q9H0Y0

Pathways: ER-Nucleus Signaling, Autophagie