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CD11b Protein (Fc Tag)

ITGAM Spezies: Human Wirt: HEK-293 Cells Recombinant
Produktnummer ABIN6964128
  • Target Alle CD11b (ITGAM) Proteine anzeigen
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Protein-Typ
    Recombinant
    Spezies
    • 10
    • 4
    • 4
    • 1
    Human
    Quelle
    • 10
    • 4
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CD11b Protein ist gelabelt mit Fc Tag.
    Sequenz
    ITGAM(Phe17-Asn1104)+hFc(Glu99-Ala330)
    Produktmerkmale
    Tagged Protein: C-Human Fc tag
    Aufreinigung
    affinity purification
    Top Product
    Discover our top product ITGAM Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Konservierungsmittel
    Without preservative
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    Haltbarkeit
    12 months
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Andere Bezeichnung
    ITGAM (ITGAM Produkte)
    Synonyme
    CD11b/CD18 Protein, CR3 Protein, CR3A Protein, Cd11b Protein, F730045J24Rik Protein, Ly-40 Protein, MAC1 Protein, Mac-1 Protein, Mac-1a Protein, CD11B Protein, MAC-1 Protein, MAC1A Protein, MO1A Protein, SLEB6 Protein, C3bi Protein, integrin subunit alpha M Protein, integrin alpha M Protein, integrin, alpha M (complement component 3 receptor 3 subunit) Protein, integrin alpha-M Protein, ITGAM Protein, Itgam Protein, LOC100351865 Protein
    Hintergrund
    Synonymes: CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6
    Description: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht
    145.2 kDa
    UniProt
    P11215
    Pathways
    Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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