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IL4 Receptor Protein (AA 26-232) (Fc Tag)

IL4R Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN6809937
  • Target Alle IL4 Receptor (IL4R) Proteine anzeigen
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 26-232
    Spezies
    • 22
    • 11
    • 7
    • 5
    • 4
    • 1
    Human
    Quelle
    • 22
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses IL4 Receptor Protein ist gelabelt mit Fc Tag.
    Sequenz
    AA 26-232
    Reinheit
    >95 % as determined by SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL4R Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
  • Target
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    Andere Bezeichnung
    IL-4 R alpha (IL4R Produkte)
    Synonyme
    IL4R Protein, il-4ra Protein, zgc:113063 Protein, CD124 Protein, IL-4RA Protein, IL4RA Protein, Il4ra Protein, IL4 Protein, Il4r Protein, interleukin 4 receptor Protein, interleukin 4 receptor, tandem duplicate 1 Protein, interleukin 4 receptor, alpha Protein, IL4R Protein, il4r.1 Protein, Il4r Protein, Il4ra Protein
    Hintergrund
    IL-4 R alpha is also known as IL4R, CD124, IL-4RA.This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE antibody production in B cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitis, asthma, or eczema. The binding of IL-4 or IL-13 to the IL-4 receptor on the surface of macrophages results in the alternative activation of those macrophages. Interleukin-4 receptor has been shown to interact with SHC1.
    Molekulargewicht
    50.4 kDa
    NCBI Accession
    NP_000409
    Pathways
    JAK-STAT Signalweg, Positive Regulation of Immune Effector Process
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