IL4 Receptor Produkte
(Interleukin 4 Receptor (IL4R))
Kategorien
This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012].
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Ausgewählte IL4 Receptor Kategorien
IL4 Receptor Antikörper
High quality antibodies with extensive validation data.
IL4 Receptor ELISA Kits
Reliable ELISA kits for a wide range of species.
IL4 Receptor Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene IL4 Receptor Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7434557
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7443335
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, FACS, ICC, IF (p), IHC (p)
Validierungen
- (2)
- (3)
Kat. Nr.
ABIN740565
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene IL4 Receptor ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (7)
- (1)
Kat. Nr.
ABIN6957153
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380459
Menge
2 x 96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4883422
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene IL4 Receptor Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN7274993
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cynomolgus
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN7274989
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7274992
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren IL4 Receptor Produkten
: "Neutrophil Extracellular Traps Reprogram IL-4/GM-CSF-Induced Monocyte Differentiation to Anti-inflammatory Macrophages." in: Frontiers in immunology, Vol. 8, pp. 523, (2017) (PubMed).: "Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue." in: Acta neuropathologica communications, Vol. 4, Issue 1, pp. 100, (2016) (PubMed).
: "Mast cells boost myeloid-derived suppressor cell activity and contribute to the development of tumor-favoring microenvironment." in: Cancer immunology research, Vol. 3, Issue 1, pp. 85-95, (2015) (PubMed).
: "PAR-2, IL-4R, TGF-? and TNF-? in bronchoalveolar lavage distinguishes extrinsic allergic alveolitis from sarcoidosis." in: Experimental and therapeutic medicine, Vol. 8, Issue 2, pp. 533-538, (2014) (PubMed).
: "Absence of a role for interleukin-13 in inflammatory bowel disease." in: European journal of immunology, Vol. 44, Issue 2, pp. 370-85, (2014) (PubMed).
: "IL-4 and IL-13 differentially regulate TLR-induced eosinophil-basophil differentiation of cord blood CD34+ progenitor cells." in: PLoS ONE, Vol. 9, Issue 6, pp. e100734, (2014) (PubMed).
: "Role of interleukin 4 and its receptor in clinical presentation of chronic extrinsic allergic alveolitis: a pilot study." in: Multidisciplinary respiratory medicine, Vol. 8, Issue 1, pp. 35, (2013) (PubMed).
: "Biomarkers of fibroproliferative healing in fibrosing idiopathic interstitial pneumonias." in: The open respiratory medicine journal, Vol. 6, pp. 160-4, (2013) (PubMed).
: "Construction and application of elastin like polypeptide containing IL-4 receptor targeting peptide." in: PLoS ONE, Vol. 8, Issue 12, pp. e81891, (2013) (PubMed).
: "Platelet ITAM signaling is critical for vascular integrity in inflammation." in: The Journal of clinical investigation, Vol. 123, Issue 2, pp. 908-16, (2013) (PubMed).
Synonyme und alternative Namen zu IL4 Receptor
interleukin 4 receptor (IL4R), interleukin 4 receptor, tandem duplicate 1 (il4r.1), interleukin 4 receptor (Il4r), interleukin 4 receptor, alpha (Il4ra), CD124, il-4ra, IL-4RA, IL4, IL4R, Il4r, IL4RA, Il4ra, zgc:113063Bezeichner auf Proteinebene für IL4 Receptor
- interleukin 4 receptor alpha chain
- interleukin-4 receptor alpha chain
- interleukin-4 receptor subunit alpha
- interleukin 4 receptor
- IL-4RA-like protein 1
- il-4alpha
- interleukin 4 receptor alpha
- soluble IL-4 receptor alpha
- interleukin-4 receptor subunit alpha-like
- IL-4 receptor subunit alpha
- IL4R nirs variant 1
- IL-4R subunit alpha
- IL-4R-alpha
- IL-4RA
- interleukin 4 receptor, alpha
- interleukin 4 tv3
- interleukin 4 tv5
- interleukin-4 receptor alpha-chain
- IL-4 receptor alpha chain
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