IL6RA Produkte
(Interleukin 6 Receptor, alpha (IL6RA))
Kategorien
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011].
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Ausgewählte IL6RA Kategorien
IL6RA Antikörper
High quality antibodies with extensive validation data.
IL6RA ELISA Kits
Reliable ELISA kits for a wide range of species.
IL6RA Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene IL6RA Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
FACS, IF (cc), IF (p), ELISA, IHC (fro), IHC (p)
Validierungen
- (2)
- (2)
Kat. Nr.
ABIN734693
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB
Validierungen
- (1)
Kat. Nr.
ABIN3181401
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
ELISA, IHC (fro), IHC (p)
Validierungen
Kat. Nr.
ABIN734695
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene IL6RA ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968019
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6719752
Menge
1 kit
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1138704
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene IL6RA Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN7275036
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN7275037
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275024
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren IL6RA Produkten
: "STAT-3-independent production of IL-17 by mouse innate-like αβ T cells controls ocular infection." in: The Journal of experimental medicine, Vol. 215, Issue 4, pp. 1079-1090, (2019) (PubMed).: "Macrophagic control of the response to uropathogenic E. coli infection by regulation of iron retention in an IL-6-dependent manner." in: Immunity, inflammation and disease, Vol. 4, Issue 4, pp. 413-426, (2018) (PubMed).
: "Leucine-rich alpha 2 glycoprotein promotes Th17 differentiation and collagen-induced arthritis in mice through enhancement of TGF-β-Smad2 signaling in naïve helper T cells." in: Arthritis research & therapy, Vol. 19, Issue 1, pp. 137, (2017) (PubMed).
: "Distinct Effects of IL-6 Classic and Trans-Signaling in Bone Fracture Healing." in: The American journal of pathology, Vol. 188, Issue 2, pp. 474-490, (2017) (PubMed).
: "Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling." in: Scientific reports, Vol. 7, pp. 44053, (2017) (PubMed).
: "Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130." in: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 121, (2017) (PubMed).
: "IL-6 trans-signaling is another pathway to upregulate Osteopontin." in: Cytokine, Vol. 90, pp. 88-95, (2016) (PubMed).
: "Comparative Ability of Mesenchymal Stromal Cells from Different Tissues to Limit Neutrophil Recruitment to Inflamed Endothelium." in: PLoS ONE, Vol. 11, Issue 5, pp. e0155161, (2016) (PubMed).
: "Vitamin D regulates cytokine patterns secreted by dendritic cells to promote differentiation of IL-22-producing T cells." in: PLoS ONE, Vol. 10, Issue 6, pp. e0130395, (2015) (PubMed).
: "Easy and rapid binding assay for functional analysis of disulfide-containing peptides by a pull-down method using a puromycin-linker and a cell-free translation system." in: Biology, Vol. 4, Issue 1, pp. 161-72, (2015) (PubMed).
Synonyme und alternative Namen zu IL6RA
interleukin 6 receptor (Il6r), interleukin 6 receptor (IL6R), interleukin 6 receptor, alpha (Il6ra), CD126, gp80, IL-6R, IL-6R-1, IL-6RA, IL6Q, Il6r, IL6R1, Il6ra, IL6RA, IL6RQBezeichner auf Proteinebene für IL6RA
- IL-6 receptor subunit alpha
- IL-6R 1
- IL-6R subunit alpha
- IL-6R-alpha
- IL-6RA
- interleukin 6 receptor, alpha
- interleukin-6 receptor subunit alpha
- CD126 antigen
- membrane glycoprotein 80
- IL-6 receptor alpha chain
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