CDKN1B Protein (AA 1-198) (His tag)

Produktnummer ABIN667591

Produktdetails

Target: CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-198

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CDKN1B Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: CDKN1B, 1-198aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol

Lagerung: 4 °C

Antigendetails

Target: CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))

Andere Bezeichnung: CDKN1B (CDKN1B Produkte)

Synonyme: CDKN4 Protein, KIP1 Protein, MEN1B Protein, MEN4 Protein, P27KIP1 Protein, cdkn1b Protein, sb:cb611 Protein, wu:fb63g10 Protein, wu:fb64g10 Protein, wu:fe18e03 Protein, CDKN1B Protein, Kip1 Protein, p27 Protein, FAM14D Protein, ISG12 Protein, ISG12A Protein, P27 Protein, Cdki1b Protein, AA408329 Protein, AI843786 Protein, p27Kip1 Protein, cdkn1bl Protein, cyclin dependent kinase inhibitor 1B Protein, cyclin-dependent kinase inhibitor 1Bb Protein, interferon alpha inducible protein 27 Protein, cyclin-dependent kinase inhibitor 1B Protein, cyclin-dependent kinase inhibitor 1Ba Protein, CDKN1B Protein, cdkn1bb Protein, IFI27 Protein, Cdkn1b Protein, cdkn1ba Protein

Hintergrund: CDKN1B, also known as cyclin-dependent kinase inhibitor 1B, belongs to the Cip/Kip family of cyclin dependent kinase (Cdk) inhibitor proteins. This protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. It is often referred to as a cell cycle inhibitor protein because its major function is to stop or slow down the cell division cycle. Recombinant human CDKN1B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Cyclin-dependent kinase inhibitor 1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1. NCBI no.: NP_004055

Molekulargewicht: 24.2 kDa (218aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Pathways: Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagie