ATG5 Protein (AA 1-275) (His tag)

Produktnummer ABIN667343

Produktdetails

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-275

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ATG5 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: ATG5, 1-275aa, Human, His tag, E.coli

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol, 0.2M NaCl

Lagerung: 4 °C

Antigendetails

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Andere Bezeichnung: ATG5 (ATG5 Produkte)

Synonyme: APG5 Protein, APG5-LIKE Protein, APG5L Protein, ASP Protein, hAPG5 Protein, ATG5 Protein, CG1643 Protein, DmAtg5 Protein, Dmel\\CG1643 Protein, atg5 Protein, 2010107M05Rik Protein, 3110067M24Rik Protein, AW319544 Protein, Apg5l Protein, Atg5l Protein, C88337 Protein, Paddy Protein, apg5l Protein, zgc:100934 Protein, ATATG5 Protein, AUTOPHAGY 5 Protein, MKP11.20 Protein, MKP11_20 Protein, autophagy related 5 Protein, Autophagy-related 5 Protein, ATG5 autophagy related 5 homolog (S. cerevisiae) Protein, autophagy related 5 L homeolog Protein, similar to S. cerevisiae ATG5 (YPL149W) which nucleates preautophagosome formation as a conjugate with Atg12 Protein, autophagy protein Apg5 family Protein, ATG5 Protein, Atg5 Protein, atg5 Protein, atg5.L Protein, APG5 Protein

Hintergrund: Autophagy protein 5, also known as ATG5, belongs to the autophagy-related (ATG) genes family. Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. ATG5 protein is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form autophagosomes. ATG5 also plays an important role in the apoptotic process. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Recombinant human ATG5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Autophagy protein 5, APG5, APG5-LIKE, APG5L, ASP, hAPG5. NCBI no.: NP_004840

Molekulargewicht: 34.6 kDa (295aa), confirmed by MALDI-TOF

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagie