STAT1 Protein (full length) (His tag)

Produktnummer ABIN622295

Produktdetails

Target: STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))

Protein-Typ: Recombinant

Proteineigenschaft: full length

Spezies: Human

Wirt: Bitte anfragen

Aufreinigungstag / Konjugat: Dieses STAT1 Protein ist gelabelt mit His tag.

Produktmerkmale: Recombinant Human STAT1

Reinheit: > 95.0 % as determined by SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized protein with no additives.

Lagerung: 4 °C

Antigendetails

Target: STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))

Andere Bezeichnung: STAT1 (STAT1 Produkte)

Synonyme: CANDF7 Protein, ISGF-3 Protein, STAT91 Protein, 2010005J02Rik Protein, AA408197 Protein, XStat1 Protein, STAT4 Protein, DD6G4-4 Protein, STAT Protein, STAT1 Protein, dZ182H3.3 Protein, si:by134g18.2 Protein, si:by51f19.1 Protein, si:dz182h3.3 Protein, si:dz199m19.1 Protein, si:dz73o4.2 Protein, stat1 Protein, signal transducer and activator of transcription 1 Protein, signal transducer and activator of transcription 1 L homeolog Protein, signal transducer and activator of transcription 1, 91kDa Protein, signal transducer and activator of transcription 4 Protein, signal transducer and activator of transcription 1a Protein, STAT1 Protein, Stat1 Protein, stat1.L Protein, stat4 Protein, stat1a Protein

Hintergrund: STAT1 Human Recombinant produced in E. coli is a non-glycosylated polypeptide chain having a molecular mass of 90 kDa. This protein is the full-length form of the protein with an amino-terminal His-tag. The STAT1 is purified by proprietary chromatographic techniques. Introduction: STAT1 is a member of the Signal Transducers and Activators of Transcription family of transcription factors. STAT1 is involved in upregulating genes due to a signal by either type I, type II or type III interferons. In response to IFN-γ stimulation, STAT1 forms homodimers or heterodimers with STAT3 that bind to the GAS (Interferon-Gamma Activated Sequence) promoter element, in response to either IFN-alpha or IFN-beta stimulation, STAT1 forms a heterodimer with STAT2 that can bind the ISRE (Interferon Stimulated Response Element) promoter element. In either case, binding of the promoter element leads to an increased expression of ISG (Interferon Stimulated Genes). Synonyms: Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84, STAT1, ISGF-3, STAT91, DKFZp686B04100.

Pathways: JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events