RPS6KB1 Protein (AA 1-525) (His tag)

Produktnummer ABIN5855088

Produktdetails

Target: RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-525

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses RPS6KB1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: ADPTHTEIKR VAEEKVTLPC HHQLGLPEKD TLDIEWLLTD NEGNQKVVIT YSSRHVYNNL TEEQKGRVAF ASNFLAGDAS LQIEPLKPSD EGRYTCKVKN SGRYVWSHVI LKVLVRPSKP KCELEGELTE GSDLTLQCES SSGTEPIVYY WQRIREKEGE DERLPPKSRI DYNHPGRVLL QNLTMSYSGL YQCTAGNEAG KESCVVRVTV QYVQSIGMVA HHHHHH

Reinheit: > 95 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1ug of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 1  mM DTT, 20 % glycerol

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))

Andere Bezeichnung: RPS6KB1 (RPS6KB1 Produkte)

Synonyme: PS6K Protein, S6K Protein, S6K-beta-1 Protein, S6K1 Protein, STK14A Protein, p70 S6KA Protein, p70(S6K)-alpha Protein, p70-S6K Protein, p70-alpha Protein, 10539 Protein, 7084 Protein, CG10539 Protein, DS6K Protein, Dmel\\CG10539 Protein, Dp70S6k Protein, Dp70[s6k] Protein, Dp70s6k Protein, S6k Protein, dS6K Protein, dS6k Protein, dp70[S6k] Protein, dp70s6k Protein, dps6k Protein, ds6k Protein, fs(3)07084 Protein, l(3)07084 Protein, p70 S6K Protein, p70/S6K Protein, p70S6K Protein, p70[S6 kinase] Protein, p70[S6K] Protein, p70[S6k] Protein, p70[S6kinase] Protein, p70s6K Protein, s6k Protein, s6k11 Protein, 2610318I15Rik Protein, 4732464A07Rik Protein, 70kDa Protein, AA959758 Protein, AI256796 Protein, AI314060 Protein, p70/85s6k Protein, p70s6k Protein, p70s6k-A Protein, p70-s6k Protein, ps6k Protein, rps6kb1 Protein, rps6kb1-A Protein, s6K1 Protein, stk14a Protein, fc51h01 Protein, wu:fc51h01 Protein, zgc:55713 Protein, ribosomal protein S6 kinase B1 Protein, Ribosomal protein S6 kinase Protein, ribosomal protein S6 kinase, polypeptide 1 Protein, ribosomal protein S6 kinase B1 L homeolog Protein, ribosomal protein S6 kinase B1 S homeolog Protein, ribosomal protein S6 kinase b, polypeptide 1b Protein, RPS6KB1 Protein, S6k Protein, Rps6kb1 Protein, rps6kb1.L Protein, rps6kb1.S Protein, rps6kb1b Protein

Hintergrund: CLMP, also known as CXADR like membrane protein, is a type 1 transmembrane protein and member of the CTX family within the immunoglobulin superfamily. This protein is highly expressed in the small intestine and placenta, and is found at intermediate levels in the heart, skeletal muscle, colon, and lung and appears in low levels in the liver and peripheral blood leukocytes as well. It is localized to junctional complexes between endothelial and epithelial cells and may play a role in cell-cell adhesion. Also, it plays a role in adipocyte differentiation and development of obesity. Recombinant human CLMP, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 25.6kDa (226aa) 28-40kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_079045

UniProt: Q9H6B4

Pathways: PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Regulation of Cell Size, Skeletal Muscle Fiber Development, Feeding Behaviour, G-protein mediated Events, Smooth Muscle Cell Migration, Interaction of EGFR with phospholipase C-gamma, Warburg Effekt