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Glypican 3 Protein (GPC3) (AA 25-559) (His tag)
GPC3
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
> 90 % by SDS - PAGE
SDS
Produktnummer ABIN5854889
Produktdetails
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Target
Alle Glypican 3 (GPC3) Proteine anzeigen
Glypican 3 (GPC3)
Protein-Typ
Recombinant
Proteineigenschaft
AA 25-559
Spezies
Alle Spezies für Glypican 3 Proteine
Human
Quelle
Alle Expressionssysteme für Glypican 3 Proteine
Baculovirus infected Insect Cells
Aufreinigungstag / Konjugat
Dieses Glypican 3 Protein ist gelabelt mit His tag.
Applikation
SDS-PAGE (SDS)
Sequenz
ADPQPPPPPP DATCHQVRSF FQRLQPGLKW VPETPVPGSD LQVCLPKGPT CCSRKMEEKY QLTARLNMEQ LLQSASMELK FLIIQNAAVF QEAFEIVVRH AKNYTNAMFK NNYPSLTPQA FEFVGEFFTD VSLYILGSDI NVDDMVNELF DSLFPVIYTQ LMNPGLPDSA LDINECLRGA RRDLKVFGNF PKLIMTQVSK SLQVTRIFLQ ALNLGIEVIN TTDHLKFSKD CGRMLTRMWY CSYCQGLMMV KPCGGYCNVV MQGCMAGVVE IDKYWREYIL SLEELVNGMY RIYDMENVLL GLFSTIHDSI QYVQKNAGKL TTTIGKLCAH SQQRQYRSAY YPEDLFIDKK VLKVAHVEHE ETLSSRRREL IQKLKSFISF YSALPGYICS HSPVAENDTL CWNGQELVER YSQKAARNGM KNQFNLHELK MKGPEPVVSQ IIDKLKHINQ LLRTMSMPKG RVLDKNLDEE GFESGDCGDD EDECIGGSGD GMIKVKNQLR FLAELAYDLD VDDAPGNSQQ ATPKDNEIST FHNLGNVHHH HHHH
Reinheit
> 90 % by SDS - PAGE
Endotoxin-Niveau
< 1.0 EU per 1 microgram of protein (determined by LAL method)
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.5 mg/mL
Buffer
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
Lagerung
4 °C,-20 °C,-80 °C
Informationen zur Lagerung
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Antigendetails
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Target
Glypican 3 (GPC3)
Andere Bezeichnung
GPC3 (GPC3 Produkte )
Synonyme
GPC3 Protein, sgb Protein, dgsx Protein, sdys Protein, sgbs Protein, oci-5 Protein, sgbs1 Protein, DGSX Protein, GTR2-2 Protein, MXR7 Protein, OCI-5 Protein, SDYS Protein, SGB Protein, SGBS Protein, SGBS1 Protein, Glypican-3 Protein, glypican 3 Protein, gpc3 Protein, GPC3 Protein, Gpc3 Protein
Hintergrund
GPC3, also known as glypican-3 isoform 2, is a member of the glypican family. It belongs to the glypican family and is highly expressed in lung, liver, and kidney. Also, it has tissue dependent. In some tissues, it acts as a tumor suppressor gene and an oncofetal protein. This protein is currently regarded as a tumor marker and potential target for immunotherapy. Recombinant human GPC3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Molekulargewicht
61.8kDa (544aa) 50-70kDa (SDS-PAGE under reducing conditions.)
NCBI Accession
NP_004475
UniProt
P51654
Pathways
Glycosaminoglycan Metabolic Process
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