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Glypican 3 Protein (GPC3) (AA 25-559) (Fc Tag)

GPC3 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE Func Active
Produktnummer ABIN4949055
  • Target Alle Glypican 3 (GPC3) Proteine anzeigen
    Glypican 3 (GPC3)
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 25-559
    Spezies
    • 24
    • 6
    • 5
    • 4
    • 1
    Cynomolgus
    Quelle
    • 26
    • 7
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Glypican 3 Protein ist gelabelt mit Fc Tag.
    Applikation
    Functional Studies (Func)
    Sequenz
    AA 25-559
    Produktmerkmale
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 87.5 kDa. GP3-C5256 may be cleaved into secrete GPC3, short propeptide (aa ?-559) & Fc tag, long propeptide (aa ?-559) & Fc tag. The protein migrates as 100 kDa (secrete GPC3 & propeptide & Fc tag), 58 kDa (long propeptide & Fc tag), 40 kDa (short propeptide & Fc tag) and 35 kDa Human IgG1 Fc fragment on a SDS-PAGE gel under reducing (R) condition.
    Reinheit
    >90 % as determined by SDS-PAGE
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product GPC3 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
  • Target
    Glypican 3 (GPC3)
    Andere Bezeichnung
    Glypican 3 (GPC3 Produkte)
    Synonyme
    GPC3 Protein, sgb Protein, dgsx Protein, sdys Protein, sgbs Protein, oci-5 Protein, sgbs1 Protein, DGSX Protein, GTR2-2 Protein, MXR7 Protein, OCI-5 Protein, SDYS Protein, SGB Protein, SGBS Protein, SGBS1 Protein, Glypican-3 Protein, glypican 3 Protein, gpc3 Protein, GPC3 Protein, Gpc3 Protein
    Hintergrund
    Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
    Molekulargewicht
    38.1 kDa and 49.4 kDa
    NCBI Accession
    XP_005594665
    Pathways
    Glycosaminoglycan Metabolic Process
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