LAMP2 Protein (AA 26-379) (His tag)

Produktnummer ABIN5854611

Produktdetails

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 26-379

Spezies: Maus

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses LAMP2 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: LIVNLTDSKG TCLYAEWEMN FTITYETTNQ TNKTITIAVP DKATHDGSSC GDDRNSAKIM IQFGFAVSWA VNFTKEASHY SIHDIVLSYN TSDSTVFPGA VAKGVHTVKN PENFKVPLDV IFKCNSVLTY NLTPVVQKYW GIHLQAFVQN GTVSKNEQVC EEDQTPTTVA PIIHTTAPST TTTLTPTSTP TPTPTPTPTV GNYSIRNGNT TCLLATMGLQ LNITEEKVPF IFNINPATTN FTGSCQPQSA QLRLNNSQIK YLDFIFAVKN EKRFYLKEVN VYMYLANGSA FNISNKNLSF WDAPLGSSYM CNKEQVLSVS RAFQINTFNL KVQPFNVTKG QYSTAQDCSA DEDNLEHHHH HH

Reinheit: > 95 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Andere Bezeichnung: Lamp2 (LAMP2 Produkte)

Synonyme: CD107b Protein, LAMP-2 Protein, LAMPB Protein, LGP110 Protein, Lamp-2 Protein, Lamp-2a Protein, Lamp-2b Protein, Lamp-2c Protein, Mac3 Protein, cd107b Protein, lamp-2 Protein, lampb Protein, LAMP2 Protein, lamp2 Protein, DKFZp459J126 Protein, LGP-B Protein, sb:cb587 Protein, wu:fb14a06 Protein, zgc:103532 Protein, lysosomal associated membrane protein 2 Protein, lysosomal-associated membrane protein 2 Protein, lysosomal-associated membrane protein 2 S homeolog Protein, lysosomal membrane glycoprotein 2 Protein, LAMP2 Protein, Lamp2 Protein, lamp2.S Protein, lamp2 Protein

Hintergrund: Lamp2, also known as lysosome-associated membrane glycoprotein 2, is a major component of lysosomal membranes. It is clinically characterized by cardiomyopathy, myopathy, and variable mental retardation. Up-regulated Lamp2 at the plasma membrane serves as an indicator of cell activation of CD8+ T cells, mast cells, monocytes, and platelets. Recombinant mouse Lamp2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 40.2kDa (362aa) 50-70KDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_001017959

UniProt: P17047

Pathways: Autophagie