LAMP2 Protein (His tag)

Produktnummer ABIN7320146

Recombinant LAMP2-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für LAMP2 Protein (His tag) (ABIN7320146)

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 97 % as determined by SDS-PAGE

Produktdetails

Aufreinigungstag / Konjugat: Dieses LAMP2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse LAMP2/CD107b Protein (His Tag)

Sequenz: Leu 26-Asn 379

Produktmerkmale: A DNA sequence encoding the mouse LAMP2 (P17047-1) extracellular domain (Leu 26-Asn 379) was fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Andere Bezeichnung: LAMP2/CD107b

Hintergrund:

Background: LAMP2 (Lysosomal-associated membrane protein 2), also known as CD107b (Cluster of Differentiation 107b), is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. In human, LAMP2, the causative gene of Danon disease, located on chromosome Xq24, encodes the lysosome-associated membrane protein-2 (LAMP-2). LAMP-2 deficiency, or Danon disease, is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation. LAMP2 cardiomyopathy is an X-linked and highly progressive myocardial storage disorder associated with diminished survival, which clinically resembles sarcomeric hypertrophic cardiomyopathy.

Synonym: CD107b,Lamp-2,Lamp-2a,Lamp-2b,Lamp-2c,LampII,LGP-B,Mac3

Molekulargewicht: 40.6 kDa

Pathways: Autophagie