JAK2 Protein (AA 1014-1132) (His tag)
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- Target Alle JAK2 Proteine anzeigen
- JAK2 (Janus Kinase 2 (JAK2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1014-1132
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses JAK2 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMGE SPIFWYAPES LTESKFSVAS DVWSFGVVLY ELFTYIEKSK SPPAEFMRMI GNDKQGQMIV FHLIELLKNN GRLPRPDGCP DEIYMIMTEC WNNNVNQRPS FRDLALRVDQ IRDNMAG
- Reinheit
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product JAK2 Protein
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Janus Kinase 2 (JAK2) (Val617Phe-Mutant) (Active) protein (GST tag)
JAK2 Spezies: Human Wirt: Insect cells (Sf21) Recombinant SDS, Func Active
Janus Kinase 2 (JAK2) (AA 826-1132) (Active) protein (His tag)JAK2 Spezies: Human Wirt: Insect cells (Sf21) Recombinant SDS, Func Active
Janus Kinase 2 (JAK2) (AA 532-1132) (Active) protein (GST tag)JAK2 Spezies: Human Wirt: Insect cells (Sf21) Recombinant SDS, Func Active
Janus Kinase 2 (JAK2) (AA 717-1132) (Active) protein (His-GST)JAK2 Spezies: Human Wirt: Insect cells (Sf9) Recombinant SDS, Func Active
Janus Kinase 2 (JAK2) (AA 241-351) protein (His-IF2DI Tag)JAK2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Janus Kinase 2 (JAK2) (AA 1-1132) protein (Strep Tag)Crystallography grade JAK2 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Janus Kinase 2 (JAK2) (AA 1-1129) protein (His tag)Crystallography grade JAK2 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Denatured
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.0 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing , 10 % glycerol, 0.4M urea
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- JAK2 (Janus Kinase 2 (JAK2))
- Andere Bezeichnung
- JAK2 (JAK2 Produkte)
- Synonyme
- JAK2bCA Protein, jak2 Protein, JTK10 Protein, THCYT3 Protein, AI504024 Protein, C81284 Protein, Fd17 Protein, JAK-2 Protein, Janus kinase 2b Protein, Janus kinase 2 Protein, jak2b Protein, JAK2 Protein, Jak2 Protein
- Hintergrund
- JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. Recombinant human Jak2 protein, fused to His-tag at N-terminus, was expressed in E.coli
- Molekulargewicht
- 18.1kDa (157aa)
- NCBI Accession
- NP_004963
- UniProt
- O60674
- Pathways
- JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
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