BIRC2 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2723209

Produktdetails

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses BIRC2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human IAP2 / BIRC2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Andere Bezeichnung: Iap2,birc2 (BIRC2 Produkte)

Synonyme: API1 Protein, HIAP2 Protein, Hiap-2 Protein, MIHB Protein, RNF48 Protein, c-IAP1 Protein, cIAP1 Protein, Api2 Protein, rIAP1 Protein, IAP1 Protein, ITA Protein, AW146227 Protein, Api1 Protein, Birc3 Protein, HIAP1 Protein, IAP2 Protein, MIAP1 Protein, MIAP2 Protein, MIHC Protein, cIAP2 Protein, mcIAP1 Protein, ciap-1 Protein, birc3 Protein, api1 Protein, birc2 Protein, c-iap1 Protein, ciap1 Protein, hiap-2 Protein, hiap2 Protein, mihb Protein, rnf48 Protein, baculoviral IAP repeat containing 2 Protein, baculoviral IAP repeat-containing 2 Protein, baculoviral IAP repeat containing 2 L homeolog Protein, BIRC2 Protein, Birc2 Protein, birc2 Protein, birc2.L Protein

Hintergrund: The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 69.7 kDa

NCBI Accession: NP_001157

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades