RASGRF1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2712357

Produktdetails

Target: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RASGRF1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human RASGRF1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Andere Bezeichnung: Rasgrf1 (RASGRF1 Produkte)

Synonyme: CDC25 Protein, CDC25L Protein, GNRP Protein, GRF1 Protein, GRF55 Protein, H-GRF55 Protein, PP13187 Protein, ras-GRF1 Protein, AI844718 Protein, CDC25Mm Protein, Grf1 Protein, Grfbeta Protein, P190-A Protein, Ras-GRF1 Protein, p190 Protein, p190RhoGEF Protein, cdc25 Protein, rasgrf1 Protein, Ras protein specific guanine nucleotide releasing factor 1 Protein, RAS protein-specific guanine nucleotide-releasing factor 1 Protein, Ras protein specific guanine nucleotide releasing factor 1 S homeolog Protein, si:ch211-234p18.3 Protein, RASGRF1 Protein, Rasgrf1 Protein, rasgrf1.S Protein, si:ch211-234p18.3 Protein, rasgrf1 Protein

Hintergrund: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molekulargewicht: 145.1 kDa

NCBI Accession: NP_002882

Pathways: RTK Signalweg, Zellzyklus, M Phase