RSPO1 Protein (His tag)

Produktnummer ABIN2566898

Produktdetails

Target: RSPO1 (R-Spondin 1 (RSPO1))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RSPO1 Protein ist gelabelt mit His tag.

Applikation: Western Blotting (WB), ELISA

Produktmerkmale:

Measured by its binding ability in a functional ELISA. Immobilized human RSPO1 at 20 μg/mL (100 μL/well ) can bind human LIMPII with a linear ranger of 31. 25 - 1000 ng/mL.

Reinheit: >95 % as determined by SDS-PAGE.

Anwendungsinformationen

Applikationshinweise: This recombinant protein can be used for WB, ELISA. For research use only.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -80 °C,-20 °C

Informationen zur Lagerung: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.

Antigendetails

Target: RSPO1 (R-Spondin 1 (RSPO1))

Andere Bezeichnung: Rspondin 1 (RSPO1 Produkte)

Synonyme: RGD1565558 Protein, CRISTIN3 Protein, RSPO Protein, R-spondin Protein, Rspondin Protein, wu:fj81e05 Protein, zgc:92153 Protein, R-spondin 1 Protein, Rspo1 Protein, RSPO1 Protein, LOC100049655 Protein, rspo1 Protein

Hintergrund: R-spondin-1 is also known as Roof plate-specific Spondin 1 (RSPO1) and cysteinerich and single thrombospondin domain containing protein 3 (Cristin 3), which is a secreted protein which belongs to the R-Spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. All Rspondins regulate Wnt/β-catenin signaling, but have distinct expression patterns. Like other R-Spondins, R-Spondin-1 contains two adjacent cysteinerich furinlike domains (aa 34-135) with one potential N-glycosylation site, followed by a thrombospondin (TSP1) motif (aa 147-207) and a region rich in basic residues (aa 211-263). Only the furinlike domains are needed for β-catenin stabilization. A putative nuclear localization signal at the C-terminus may allow some expression in the nucleus.

Molekulargewicht: 27.6 kDa

Gen-ID: 284654

UniProt: Q2MKA7