IRAK1 Protein (AA 618-712) (His tag)
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- Target Alle IRAK1 Proteine anzeigen
- IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 618-712
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses IRAK1 Protein ist gelabelt mit His tag.
- Applikation
- Western Blotting (WB), ELISA, Mass Spectrometry (MS), Neutralization (Neut)
- Reinheit
- ~95 %
- Top Product
- Discover our top product IRAK1 Protein
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Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 194-712) (Active) protein (GST tag)
IRAK1 Spezies: Human Wirt: Insect cells (Sf21) Recombinant SDS, Func Active
Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 504-712) protein (GST tag)IRAK1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 1-633) protein (GST tag)IRAK1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 530-693) protein (GST tag)IRAK1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 1-712) protein (Strep Tag)Crystallography grade IRAK1 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 1-710) protein (Strep Tag)Crystallography grade IRAK1 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)IRAK1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Applikationshinweise
- This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- 100 mM sodium phosphate, 500 mM NaCl, 25 mM imidazole, 10 % gycerol
- Handhabung
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store in working aliquots at -70 °C.
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- Target
- IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
- Andere Bezeichnung
- IRAK (IRAK1 Produkte)
- Synonyme
- IRAK1 Protein, IRAK Protein, pelle Protein, AA408924 Protein, IRAK-1 Protein, IRAK1-S Protein, Il1rak Protein, Plpk Protein, mPLK Protein, RGD1563841 Protein, interleukin 1 receptor associated kinase 1 Protein, interleukin-1 receptor-associated kinase 1 Protein, IRAK1 Protein, irak1 Protein, Irak1 Protein
- Hintergrund
- Nuclear factor kappa B (NF-?B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-?B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNF? and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently (1,2). IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response (3). IRAK mediates a signaling cascade leading to NF-?B activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF) (1,4).
- Molekulargewicht
- 15 kDa (Calculated)
- Gen-ID
- 3654
- OMIM
- 8928535
- UniProt
- P51617
- Pathways
- NF-kappaB Signalweg, TLR Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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