CD25 Protein (AA 22-213) (His tag)
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- Target Alle CD25 (IL2RA) Proteine anzeigen
- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 22-213
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Spezies
- Human
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Quelle
- HEK-293T Cells
- Aufreinigungstag / Konjugat
- Dieses CD25 Protein ist gelabelt mit His tag.
- Produktmerkmale
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Determined by its ability to increase the proliferation effect of IL-2 in murine CTLL-2 cells. In the presence of 1 ng/mL of recombinant IL-2, ED50 for this effect is < 1.5 μg/mL.
AA 22-213, expressed with N-terminal 8xHis - Reinheit
- > 95 % as analyzed by SDS-PAGE and HPLC.
- Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL2RA Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Lyophilized recombinant Human Interleukin-2 Receptor alpha remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interleukin-2 Receptor alpha should be stable up to 1 week at 4 °C or up to 3 months at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
- Andere Bezeichnung
- Interleukin-2 Receptor Alpha(IL-2 R Alpha) (IL2RA Produkte)
- Synonyme
- CD25 Protein, IDDM10 Protein, IL2R Protein, TCGFR Protein, IL2RAC Protein, IL-2RA Protein, Il2r Protein, Ly-43 Protein, interleukin 2 receptor subunit alpha Protein, interleukin-2 receptor subunit alpha-like Protein, interleukin 2 receptor, alpha chain Protein, IL2RA Protein, Il2ra Protein, LOC100222957 Protein
- Hintergrund
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Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to the cytokine IL-2. The IL-2R is made up of 3 subunits - alpha , beta and gamma . The alpha and beta chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the gamma-chain, along with the beta subunit. The beta and gamma chains of the IL-2R are members of the type I cytokine receptor family. IL-2R has a high binding affinity to IL-2 and is expressed by antigen-activated T lymphocytes (T cells). IL-2 R alpha is also known as CD25, p55, and Tac (activated T cell) antigen.Recombinant Human Interleukin-2 Receptor alpha (IL-2 R alpha), His produced in HEK 293 cells is a polypeptide chain containing 205 amino acids. A fully biologically active molecule, rhIL-2 R alpha has a molecular mass of 42 kDa analyzed by reducing SDS-PAGE.
Synonyms: soluble IL-2 receptor, TAC-antigen, CD25 antigen - Molekulargewicht
- 42 kDa, observed by reducing SDS-PAGE.
- UniProt
- P01589
- Pathways
- JAK-STAT Signalweg, Growth Factor Binding, Activated T Cell Proliferation
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