TNFRSF10B Protein (AA 52-212, Extracellular Domain) (Fc Tag)
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- Target Alle TNFRSF10B Proteine anzeigen
- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- Extracellular Domain, AA 52-212
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Spezies
- Human, Maus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses TNFRSF10B Protein ist gelabelt mit Fc Tag.
- Applikation
- SDS-PAGE (SDS)
- Spezifität
- Binds to human and mouse TRAIL.
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
- The extracellular domain of human TRAIL-R2 (aa 52-212) is fused to the Fc portion of human IgG1.
- Reinheit
- >95 % (SDS-PAGE)
- Endotoxin-Niveau
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product TNFRSF10B Protein
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Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) protein (His-Avi Tag,Biotin)
TNFRSF10B Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 53-180) protein (His tag)TNFRSF10B Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-182) protein (His-Avi Tag)TNFRSF10B Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-182) protein (Fc Tag)TNFRSF10B Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) protein (mFc Tag)TNFRSF10B Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-180) protein (His-DYKDDDDK-Strep II Tag)TNFRSF10B Spezies: Human Wirt: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-210) protein (His-DYKDDDDK-Strep II Tag)TNFRSF10B Spezies: Human Wirt: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-182) (Active) protein (Fc Tag)TNFRSF10B Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (Active) proteinTNFRSF10B Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 52-183) protein (His tag)TNFRSF10B Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Blocks human or mouse TRAIL activity in a concentration of 1-10μg/ml.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with 50 μL sterile water.
- Konzentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Haltbarkeit
- 6 months
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- Target
- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
- Andere Bezeichnung
- TRAIL-R2 (TNFRSF10B Produkte)
- Synonyme
- TNFRSF10B Protein, dr5 Protein, cd262 Protein, killer Protein, trick2 Protein, trickb Protein, xDR-M1 Protein, xDR-M2 Protein, ztnfr9 Protein, trailr2 Protein, trick2a Protein, trick2b Protein, CD262 Protein, DR5 Protein, KILLER Protein, KILLER/DR5 Protein, TRAIL-R2 Protein, TRAILR2 Protein, TRICK2 Protein, TRICK2A Protein, TRICK2B Protein, TRICKB Protein, ZTNFR9 Protein, Ly98 Protein, MK Protein, tumor necrosis factor receptor superfamily, member 10b Protein, tumor necrosis factor receptor superfamily member 10b S homeolog Protein, tumor necrosis factor receptor superfamily member 10b L homeolog Protein, tumor necrosis factor receptor superfamily member 10b Protein, TNF receptor superfamily member 10b Protein, Tnfrsf10b Protein, TNFRSF10B Protein, tnfrsf10b.S Protein, tnfrsf10b.L Protein, tnfrsf10b Protein
- Hintergrund
- TRAIL-R2 (DR5, CD262) is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
- Molekulargewicht
- ~50kDa (SDS-PAGE)
- UniProt
- O14763
- Pathways
- p53 Signalweg, Apoptose, Positive Regulation of Endopeptidase Activity
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