MYD88 Protein (His tag)
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- Target Alle MYD88 Proteine anzeigen
- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses MYD88 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Reinheit
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product MYD88 Protein
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- Kommentare
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Synonyms: Myeloid differentiation primary response protein MyD88, MYD88D
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M urea, 10% glycerol
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Avoid repeated freezing and thawing cycles.
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- Target
- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
- Andere Bezeichnung
- MYD88 (MYD88 Produkte)
- Synonyme
- MYD88D Protein, XMyD88 Protein, myd88d Protein, MGC84928 Protein, CG2078 Protein, DMMYD88 Protein, DmMyD88 Protein, DmMyd88 Protein, Dmel\\CG2078 Protein, EP(2)2535 Protein, Kra Protein, LD20892 Protein, MYD88 Protein, MyD88 Protein, Myd88F Protein, dMyD88 Protein, dMyd88 Protein, kra Protein, myd88 Protein, zgc:103541 Protein, GB12344 Protein, NV10640 Protein, myd88-a Protein, myd88-b Protein, myeloid differentiation primary response 88 Protein, myeloid differentiation primary response 88 S homeolog Protein, myeloid differentiation primary response gene 88 Protein, CG2078 gene product from transcript CG2078-RB Protein, myeloid differentiation primary response protein MyD88-A Protein, myeloid differentiation primary response protein MyD88 Protein, myeloid differentiation factor 88 Protein, myeloid differentiation primary response 88 L homeolog Protein, MYD88 Protein, myd88.S Protein, Myd88 Protein, myd88 Protein, LOC413194 Protein, LOC100118553 Protein, LOC575153 Protein, myd88.L Protein
- Hintergrund
- Myeloid differentiation primary response gene 88, also known as MYD88, acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. This protein increases IL-8 transcription. It is involved in IL-18-mediated signaling pathway. MYD88 activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. Recombinant human MYD88 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molekulargewicht
- 38.7kDa (345aa)
- NCBI Accession
- NP_002459
- Pathways
- NF-kappaB Signalweg, TLR Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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