anti-Maus PIP5K1C Antikörper für Immunofluorescence

Recommended PIP5K1C Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) Antikörper
  • LCCS3
  • PIP5K-GAMMA
  • PIP5Kgamma
  • PIPKIg_v4
  • MGC130766
  • PIP5K1C
  • pip5k1a
  • zgc:110576
  • AI115456
  • AI835305
  • Pip5kIgamma
  • phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
  • phosphatidylinositol-4-phosphate 5-kinase, type I, gamma S homeolog
  • phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
  • phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a
  • phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma
  • PIP5K1C
  • Pip5k1c
  • pip5k1c.S
  • pip5k1aa
  • pip5k1c
Epitop
AA 479-580
8
8
3
3
3
3
2
2
2
2
2
1
1
1
Reaktivität
Maus, Ratte (Rattus)
43
8
6
3
Wirt
Maus
38
5
Klonalität
Monoklonal
Konjugat
Dieser PIP5K1C Antikörper ist unkonjugiert
2
2
2
2
2
2
Applikation
Immunofluorescence (IF), Western Blotting (WB)
40
26
18
6
2
2
1
Optionen
Hersteller
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Produktnummer ABIN968393
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General

Antigen Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) Antikörper
Epitop AA 479-580
(8), (8), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1)
Reaktivität Maus, Ratte (Rattus)
(43), (8), (6), (3)
Wirt Maus
(38), (5)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser PIP5K1C Antikörper ist unkonjugiert
(2), (2), (2), (2), (2), (2)
Applikation Immunofluorescence (IF), Western Blotting (WB)
(40), (26), (18), (6), (2), (2), (1)
Pubmed 3 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-PIP5K1C Antikörper

Target Details PIP5K1C Anwendungsinformationen Handhabung Referenzen für anti-PIP5K1C Antikörper (ABIN968393) Bilder
Kreuzreaktivität Ratte (Rattus)
Produktmerkmale 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Reinigung The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Mouse PIP5Kgamma aa. 479-580
Klon 12-PIP5Kgamma
Isotyp IgG1

Target Details PIP5K1C

Produktdetails anti-PIP5K1C Antikörper Anwendungsinformationen Handhabung Referenzen für anti-PIP5K1C Antikörper (ABIN968393) Bilder zurück nach oben
Antigen
Andere Bezeichnung PIP5K gamma (PIP5K1C Antibody Abstract)
Hintergrund Phosphoinositide turnover is a well established mechanism of intracellular signal transduction. Sequential phosphorylation of phosphatidylinositol (PtdIns) results in PtdIns(4)P (PIP) and PtdIns(4,5)P2 (PIP2). Phospholipase C (PLC) hydrolyzes PIP2 to inositol (1,4,5)P3 (IP3) which stimulates release of intracellular Ca2+. PIP2 is generated by phosphorylation of PtdIns 5-kinases (PI5-K). These enzymes are divided into two types (I and II) based on their size and sensitivity to certain compounds. Three mammalian PI5-Ks, PI5-Kalpha, beta, and gamma of type I have been identified and a type II PIP5kalpha. Although the PI4-Ks are abundantly distributed throughout the cell, activity is found primarily in association with membranous structures. Members of this family contain a lipid kinase unique domain and a C-terminal catalytic domain.
Molekulargewicht 87-90 kDa
Pathways PI3K-Akt Signalweg, Inositol Metabolic Process, Cell-Cell Junction Organization, Maintenance of Protein Location, Synaptic Vesicle Exocytosis

Anwendungsinformationen

Produktdetails anti-PIP5K1C Antikörper Target Details PIP5K1C Handhabung Referenzen für anti-PIP5K1C Antikörper (ABIN968393) Bilder zurück nach oben
Kommentare

Related Products: ABIN968545, ABIN967389

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-PIP5K1C Antikörper Target Details PIP5K1C Anwendungsinformationen Referenzen für anti-PIP5K1C Antikörper (ABIN968393) Bilder zurück nach oben
Format Liquid
Konzentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store undiluted at -20°C.

Referenzen für anti-PIP5K1C Antikörper (ABIN968393)

Produktdetails anti-PIP5K1C Antikörper Target Details PIP5K1C Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Ishihara, Shibasaki, Kizuki, Wada, Yazaki, Asano, Oka: "Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family." in: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8741-8, 1998

Nishikawa, Toker, Wong, Marignani, Johannes, Cantley: "Association of protein kinase Cmu with type II phosphatidylinositol 4-kinase and type I phosphatidylinositol-4-phosphate 5-kinase." in: The Journal of biological chemistry, Vol. 273, Issue 36, pp. 23126-33, 1998

Tolias, Rameh, Ishihara, Shibasaki, Chen, Prestwich, Cantley, Carpenter: "Type I phosphatidylinositol-4-phosphate 5-kinases synthesize the novel lipids phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 5-phosphate." in: The Journal of biological chemistry, Vol. 273, Issue 29, pp. 18040-6, 1998

Bilder

Produktdetails anti-PIP5K1C Antikörper Target Details PIP5K1C Anwendungsinformationen Handhabung Referenzen für anti-PIP5K1C Antikörper (ABIN968393) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) (AA 479-580) antibody (ABIN968393) Western blot analysis of PIP5Kgamma on a rat cerebrum lysate. Lane 1: 1:250, lane 2: ...
Immunofluorescence (IF) image for anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) (AA 479-580) antibody (ABIN968393) Immunofluorescence staining of PC12 cells (Rat neuroblastoma, ATCC CRL-1721).
 image for anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) (AA 479-580) antibody (ABIN968393) anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) (AA 479-580) antibody (Image 3)
Western Blotting (WB) image for anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) (AA 479-580) antibody (ABIN968393) anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) (AA 479-580) antibody (Image 4)